Bio; Lecture 09; Population Genetics

Bio; Lecture 09; Population Genetics - Principles of...

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Principles of Biology 2 BioU103 1/29/06 Population Genetics In normal situations, there is a shuffling of alleles between generations— mutations, crossing over, selective mating, etc. change the allele frequency of the gene pool of a population The Hardy Weinberg equilibrium determines the genetics of a non-evolving population. There is no change in the frequency of alleles and genotyes from parent generation to offspring generation- if conditions are met Sample Problem o In a population that is under Hardy Weinberg equilibrium, the dominant phenotype, A, is present in 96% of a population o p 2 +2pq+q 2 =1 o the frequency of the dominant phenotype AA and Aa (p 2 and 2pq) is .96 o plug in .6 for p 2 and 2pq from the H-W equation o .96 + q 2 = 1 o q 2 = .04 = aa frequency o q = .2 o p + q = 1 p + .2 = 1 p = .8 o p 2 = .8 2 = .64 = AA frequency o .64 + 2pq + .04 = 1 2pq = .32 = Aa frequency Populations at Hardy-Weinberg equilibrium must satisfy five conditions o Very large population size:
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Bio; Lecture 09; Population Genetics - Principles of...

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