Final Exam Answer Key

Final Exam Answer Key - MIBO 2500 Final Spring 2008 Dr...

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MIBO 2500 Final Spring 2008 Dr. Walker Name_________________ There are 160 points available on this test. Questions on this exam are worth 2 points. Please transfer your answer accurately from your test to your scantron since your answers will be based solely on the scantron results. 1. Once Yersinia pestis enters the body through a flea bite, it successfully causes infection by a. Disabling phagocytes b. Blocking cytokine release c. Destroying complement proteins via proteases d. Utilizing its capsule to avoid phagocytosis e. All of the above 2. The bubos that form with an infection of Yersinia pestis indicate why type of response? a. Phagocytic response via neutrophils b. Systemic inflammatory response c. Adaptive immune response d. Lytic response via natural killer cells e. Hypersensitivity type III response 3. Type III secretion system is a virulence factor in releasing exotoxins. a. True b. False 4. What portion of the antibody do Protein A of S. aureus and macrophages bind? 5. If MHC II molecules checked by a T helper cells are bound by a superantigen, what would happen? a. Viruses couldn’t infect the cell b. T helper cells couldn’t bind to the MHC I molecules on all tissue c. T cytotoxic cells couldn’t monitor for infected cells d. B cells would not produce antibodies e. More T helper cells would be activated than normal 6. Streptococcus pyogenes contains a host of virulence factors. A complication of strep throat is rheumatic fever which is thought to be brought on by inflammatory reaction to the body’s proteins mimicked by S. pyogenes . What is S. pyogenes purpose in creating surface proteins that mimic the body’s proteins? a. Induce uptake by body’s cells to hide from macrophages b. Avoid complement proteins which trigger cascade c. Utilize M cells for uptake and hide from macrophages d. Avoid being recognized by antibodies and allow bacteria to colonize e. Damage host cells A B C D
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7. Exotoxins are a. Superantigens b. Hemolysins c. Proteins d. A, B and C e. B and C 8. The excreted cholera toxin targets epithelial cells of the intestine, causing hypersecretion of Cl - ions and water loss. How would this toxin be catergorized? a. Neurotoxin b. Endotoxin c. Cytotoxin d. Enterotoxin e. Bacteriostatic 9. If you treated both the growing Neisseria meningitidis and its toxin with high heat, would you be successful in destroying both? a. Yes, because both the cell’s proteins and the toxin would denature b. Yes, because the cell would lyse and the toxin break apart c. No, an endotoxin cannot be destroyed by heat but the cell would d. No, an endospore would form and the toxin would still be produced e. No, neither cell nor toxin would be destroyed by heat 10. Which of the following DOES NOT contribute to a pathogen’s virulence? a.
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This note was uploaded on 05/15/2008 for the course MIBO 2500 taught by Professor Walker during the Spring '08 term at UGA.

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Final Exam Answer Key - MIBO 2500 Final Spring 2008 Dr...

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