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Unformatted text preview: 3/10/2008 1 Immune function and Endocrinology Immune function and Endocrinology Quiz questions: Quiz questions: 1. Which is not a lymphoid organ? A) lymph node, B) thyroid gland, or C) spleen. 2. The typical fraction of cells to plasma in blood: A) 45%, B) 55%, or C) 70%. 3. Which vessels lack muscles or check valves to augment flow A) veins B) arteries or C) to augment flow: A) veins, B) arteries, or C) lymphatic vessels. 4. Blood platelets are formed from A) RBCs, B) megakaryocytes, C) plasma, or D) WBCs 5. The most abundant type of WBC in a health human are A) eosinophils, B) monocytes, C) lymphocytes, or D) neutrophils. Immune responses: Immune responses: Neutrophils and macrophages eat cells Complement tags cells to be eaten ( but they are not specific to any one antigen ) Two other specific responses: 1) Humoral/antibody response lymphocytes produce specific antibodies- lymphocytes produce specific antibodies, which can act as tags or agglutinate- some cells are set aside as memory cells 2) Cell mediated response- lymphocytes directly attack infected cells Immune responses: Immune responses: Macrophages:- Chompers! Phagocytize cells and particles- alert helper T-cells Lymphocytes: Key players:- B-cells (mature in bone marrow) and T-cells (mature in Thymus)- hangouts: lymph nodes, spleen, appendix, other lymphoid tissue- favorite things: like to fight! Immune responses: Immune responses: B-cells:- make IgD antibodies- when activited (with help from helper T-cells) can do a variety of things: 1) produce plasma cells antibody factories! Key players: 2) produce memory cells can retain antibodies over time, ready for reinfection (2 nd immune response) faster than the 1 st ! Immune responses: Immune responses: T-cells:- Thymus secretes thymosin to activate T-cells- when activited, T-cells become: 1) Helper T-cells (T h cells) activate by binding w/ macrophages, secrete Key players: cytokines 2) Killer T-cells directly destroy tumor cells of body or those already infected 3) Suppressor T-cells control rate of immune response by binding to T-cells 4) Memory T-cells persist in body for months ready to fight reinfection 3/10/2008 2 Figure 43.10 An overview of the immune responses (Layer 4) Types of immune responses and immunity Types of immune responses and immunity 1 immune response after1 st exposure to antigen. 2 immune response after2 nd exposure to antigen Much faster because of clones antigen. Much faster because of clones and memory cells Active immunity body responds by producing antibodies to combat antigens Passive immunity introducing antibody for particular antigen into the body....
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This note was uploaded on 05/18/2008 for the course BIOL 211B taught by Professor Lowe/zahn during the Spring '08 term at CSU Long Beach.
- Spring '08