Unformatted text preview: complexes by mediating interactions between intracellular signaling proteins and associated molecules Ans: Amino acid sequence that surrounds SH2 domain. (Key and Lock anology) Cascades One ligand Interacts with Receptor Activates Effectors Many 2 nd messengers are made (amplification Transduction of Signal Effect Signaling Molecules Decreased synthesis of signal molecules=no significant change in signal molecules concentration If lifespan of signaling molecules is short then we can drastically change (inc/dec) concentration of signal molecule Allosteric Feedback Ligand binds enzyme is activated at low level substrate to product conversion after product is made it can bind back on the enzyme and up-regualte synthesis of product (reinforcement of signal)...
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- Winter '08
- cell biology, GPK, intracellular signaling proteins, Luis David Gomez, Signaling Principles Review, Signaling Molecules Decreased