W1OutlineLec3

W1OutlineLec3 - Luis David Gomez 59866865 Bio 192 D103 Cell...

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Luis David Gomez 59866865 Bio 192 D103 Cell Biology Week 1 Lecture 3 Outline 1/ 11/08 Carrier, Transports and Pumps How do molecules get across biological membrane? Integral Membran Proteins! with at least one transmembrane domoin 1. Carries/Transports 2. Pumps Ion Channels—fastest open/closed state Transporters—slower Uniporter-one molecule down concentration gradient Symporter- two binding sites transported together in SAME direction one down its concentration gradient (no energy input) one up its concentration gradient—no energy, provided by other molecule Antiporter—“ What is the difference between various structures? passive transport—no ATP, no energy takes advantage of concentration gradient 1. Carrier/Transporter specific binding sites saturable (unaffected by concentration gradient) Conformational Change (passive transport) 2. Ion Channel—H2O Aquaporins selective pore based on size driven by concentration gradient (passive transport) Blocking ions from balancing creates MEMBRAN POTENTIAL
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W1OutlineLec3 - Luis David Gomez 59866865 Bio 192 D103 Cell...

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