W2OutlineLec5

W2OutlineLec5 - Luis David Gomez 59866865 Bio 192 D103 Cell...

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Luis David Gomez 59866865 Bio 192 D103 Cell Biology Week 2 Lecture 5 Outline 1/ 16/08 Wednesday Mitochondria Food a.a, simple sugars, fatty acids (glycolysis) pyruvate, acetyl CoA ATP 1. ATP generation by Oxidative Phosphorylation Making ATP from ADP through oxations of food to CO2 leads to ELECTROCHEMICAL (Proton gradient) Drives ATP synthesis Briefly cover glycolysis—important to note need for carrier Mitos Arrangement—in a network of energy producing organelles Structure Outer membrane: very permeable to small molecules (less than 5000 KDa), porins 50% phospholipids by weight, big holes (barreles, homo-trimers) make continuous with cytoplasm --make the matrix more basic by pumping protons out! Inner membrane:Cariolipin (unusuall phosphlipid) contains 4 fatty acid chais with glycerol back bone with high protein content, makes membrane very, very tight C.Q. Why do we need so much surface area on mitos inner memrane? a)regulates CTA
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W2OutlineLec5 - Luis David Gomez 59866865 Bio 192 D103 Cell...

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