Unformatted text preview: • Thymosin-Beta4 Sequesters ATP-actin Have plenty of ATP-actin BUTbut it would be “tied up” and it would cause filament to shrink Q.Q. How does actin behave in the presence of a – end binding protein and c (cytosolic g-actin-atp less than Cc(+)? C) Because the (-) end binding protein is holding (-) end together then only the (+) end would shrink, Cc (+) is low Dynamics ARP2/3 nucleating protein: induces branching (70 degrees) polymerization of Lysteria: ActA • Necessary—if we remove it will it work? • Sufficient—if we add it will it behaive the same Examples: bacterial invasion cell locomotion...
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- Winter '08
- cell biology, 70 degrees, Luis David Gomez, Assembly Actin Treadmilling