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Unformatted text preview: amino acidsLec 15 p. 15 Prolinebackbone is kinked in a certain way, cannot rotate about a praline, important in signaling, never found in alpha helical region Summation of amino acid interactions dictate overall protein interactions with other proteins--change one or two Amino acids CONFORMATIONAL CHANGE Calmodulinbinding of Ca2+ (ligands) interacts with acidic a.a. and completely changes the structure (to cause conformational changes) affinitystrength with which someone holds on specificityselection of one ligand over another pointless to remember ALL subdomains Y(a.a.)### (location is peptide chain) gets phosphorylated p(hosphorylate hydroxyl group)A.A.#### --cannot phosphorylate one at a time, both residues much be phosphorylated at once by special kinase (adds Phosphate)...
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This note was uploaded on 05/28/2008 for the course BIOL D103 taught by Professor Suetterlin/macgregor during the Winter '08 term at UC Irvine.
- Winter '08
- cell biology