ProblemSetWk4 - C They induce actin depolymerization D They induce ATP hydrolysis in actin subunits at the end E They release factors that cause

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Bio D103: Cell Biology Bio. Department Tutoring Winter 08: Week 4 Lectures 6-8 Review 1/30/08 Wed. 1-3:00 SH157 *Hint: The (+) plus side takes less free [ATP-G-actin] concentration to add and grow. 1.) The critical concentration for the plus end of an AF is 0.12uM , while the critical concentration for the minus end is 0.18uM . At what cellular concentrations of the actin monomer pool would treadmilling occur? Explain your answer. 2.) Certain bacteria, such as Listeria monocytogenes , utilize the cell’s actin cytoskeleton for intracellular movement and infection of neighboring cells. How do these bacteria manage to take over the actin cytoskeleton of a cell? A) They secrete molecules that sequester G-actin B) They have surface proteins that nucleate actin
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Unformatted text preview: C) They induce actin depolymerization D) They induce ATP hydrolysis in actin subunits at the (-) end E) They release factors that cause myosin polymerization 3.) If the concentration of actin subunits in a cell is above the critical concentration (Cc) for the minus (-) end, A) Treadmilling would occur B) Both plus and minus ends would lose subunits C) Both plus and minus ends would gain subunits D) The actin filaments would display increased levels of dynamic instability 4.)Protrusion of actin at the leading edge of a cell involves A. Nucleation of new filaments by ARP2/3 B. Elongation of actin filaments C. Capping of actin filaments at steady state D. Recognition of the ADP-form of actin by cofilin E. All of the above...
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This note was uploaded on 05/28/2008 for the course BIO SCI D103 taught by Professor Suetterlin/macgregor during the Winter '08 term at UC Irvine.

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