{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

Required Reading #1 - Visa/u REPORT The Potential Impact on...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Background image of page 2
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Visa/u REPORT The Potential Impact on Women from Environmental Exposures Observations from the Centers for Disease Control and Prevention Je Anne R. Burg, Ph.D. Ginger L Gist, Ph.D. he Agency for Toxic Substances and Dis- ease Registry (ATSDR) has established the National Exposure Registry (NER) for the pur- pose of assessing the potential long-term health impact on the general population of exposures to environmental hazards such as those at Superfund sites. Using published policies and procedures. ATSDR has established four chemi- calospecific subregistries—trichloroethane (TCA). trichlonoethylene (TCE). benzene. and dioxin—and is following approximately 10,000 registrants longitudinally (1-6). The NER col- lects. at baseline and at ongoing biennial fol- low-ups. information on demographics; smok- ing. occupational. and reproductive histories; and 25 general health conditions. The rates of reponed health conditions are compared with national norms. The comparison results are viewed as interim or hypothesis generating. ATSDR might conduct a more in-depth study based on the findings. There is very little available information on the potential health effects of low-level ex- posures of long duration—the type of expo- sures commonly experienced at wate sites-o in a general population. Most information on the health effects of exposure to hazardous substances comes from occupational studies of healthy males and toxicologic studies in which such low-level. long-tenn environmen- tal exposures cannot be duplicated. Of particu- 50 Environmental Health ° July/August I998 lar concern is the lack of information about the impact on sensitive subpopulations. such as children. the elderly. those who are sick. and pregnant women. When environmental exposures occur. usually in the home. these sensitive subpopulatiorLs experience the great- est exposure because of the nature of their activities and the time spent in the home. The NER is addressing this paucity of relevant health information on environmentally ex- posed general populations. including sensitive subpopulations and all women, by amassing information. To date. the NER has longitudi- nal data on approximately 5.000 female regis- trants. ranging in age from infants to the eld- erly. who have documented exposure to a spe- cific hazardous substance in the environment. In addition to the baseline data collection. the NER data collection is a longitudinal effort (biennial updates) because the expected out. come for a general population—should there be one—is not known. and, therefore. the ex- pected latency is not known. Some subregistry populations have been followed since 1988. To determine if there is excess reporting of adverse health outcomes. the registrants‘ re- porting rates for 25 general health outcomes and symptom were compared (adjusted for sex and age) with national norms provided by the National Health Interview Survey. Statistically significant increases in reports of several health outcomes. that is. anemia and other blood dis- orders. skin rashes. and stroke. by select age and sex groups were found for registrants of at least one of the active subregistn'es. For other health outcomes. that is. diabetes. kidney prob- lems. liver problems. and urinary tract disor- ders, increased reports were found predomio nantly in women (Table 1). This information. supplemented with ad- ditional information from analyses of the fol- low-up data. indicates that there is excess re— porting of health problems by environmentally exposed women that might be associated with exposure to low-level hazardous substances over extended periods. A more definitive as- sessment of this association will be made us- ing the additional information and study re- sults being compiled. In some cases. ATSDR decided to carry out additional studies to ex- plore the hypotheses suggested by these baseline data results. ATSDR is very interested in sharing this information. Baseline information for the TCE subregistry is currently available from ATSDR (without personal identifiers) on CD-ROM. For additional information on these and other data from the NER. contact Je Anne R. Burg. Ph.D.. Chief. Exposure and Disease Registry Branch. ATSDR. 1600 Clifton Road, E-31.At- lanta. GA 30333. a (Reprinted from Journal of Women‘s Health Vol. 6. No.2. 1997) dew... “ . . .only 3% of the 80 million annual estimated cases of food poisoning in the us. originate in meat processing and packaging plants . . . 70% of food-related illness origi- nates at the point of prepa- ration and service.” an WW ”VB-Emma! Health 31 ...
View Full Document

{[ snackBarMessage ]}