Lecture #4: Infectious Disease Epidemiology

Lecture #4: Infectious Disease Epidemiology - Epid420 2 Top...

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Epid420 2
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Top Ten Reported Infectious Diseases of 1999 in USA 1. Chlamydia STD 2. Gonorrhea STD 3. AIDS STD / Blood 4. Salmonellosis Fecal/oral 5. Hepatitis A Fecal/oral 6. Shigellosis Fecal/oral 7. Tuberculosis Respiratory 8. Lyme Disease Arthropod 9. Hepatitis B STD / Blood 10. Syphilis STD
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The infectious disease process 1. Agents- what is causing the illness 2. Reservoirs- where the agents live 3. Portals of entry and exit 1. Transmission- how they get in and out 4. Host immunity- what factors affect disease progression
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Gradient of Host Response Inapparent Mild Moderate Severe Fatal Tuberculosis Measles Rabies
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Modes of transmission 1. Mode of transmission – any mechanism by which an agent is spread to the host 2. Some bridging between hosts or environment and host 1. Contact: Direct or Indirect contact 2. Vectors (animate objects) 3. Vehicles (inanimate objects)
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Modes of transmission 1. Contact: 1. Direct – person to person 2. Indirect – contact with relatively fresh bodily fluids or tissue 2. Common vehicle spread 1. Air, water, food, drugs – 3. Serial transfer 1. Human to human, 2. Human to animal to human, 3. Human to environment to human in sequence
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Lecture #4: Infectious Disease Epidemiology - Epid420 2 Top...

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