QS KEY Nov 16 - How to use these questions The real value...

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How to use these questions: The real value in these questions is in thinking about and discussing the reasoning behind the answers. Simply memorizing their answers is no where near as valuable. So I recommend you use these, when you study, as prompts for thought and conversation about why these answers are correct. You are interested in studying the CFTR gene, because mutations in this gene in humans cause cystic fibrosis (CF). You have a line of mice that lack the mouse CFTR gene. These mice get lung disease, similar to CF patients. Starting with some of these mice, you add a transgenic normal human CFTR gene. The resulting mice do not get the lung disease, even though they still lack the mouse CFTR gene. What can you conclude? 1. The DNA sequences of the mouse and human CFTR genes are identical. 2. The amino acid sequences of the mouse and human CFTR proteins are identical. 3. The mouse CFTR gene and the human CFTR gene encode proteins that can serve a similar function.
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