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bisc300-2005exam_susskind

bisc300-2005exam_susskind - Name 1Write yflur name at the...

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Unformatted text preview: Name 1Write yflur name at the tap of EVERY PAGE. Pages witheut names may nut receive eredit. IN ALL YOUR RESPONSES, SPELLING COUNTS Questitm l {16 paints.) Question 2 (II paints} Questinn 3 {II} points] Questinn 4 (14 points] Questien 5 {9 [mints] Question 6 [8 points} Questiun T I? paints] Quastiun 3 [16 paints] Questiuns 9-H! {7' pts.) Questians 11-13 {5 p15.) TOTAL {100 PUINTS} BISC 3M] [ntrnduetinn tu Miernhielngy MIDTERM 1 l4 Februaryr was Page 1 Susskifid’s I I I Hams: Mld’rzrm I. E/I'f'ffls. Susfil‘ffld? “I“‘ESMS 9. [3 pt, 1 pt each; nu credit if you list more than 31 .355 discussed in Class and in the text, living things have three general methods of making ATP. Please list them. The}; have to be gpelled correctly. 10. H pt, 1 pt par blank; DO NOT USE ABBREVIATIONS}. The figure below summarizes energy metabolism for many {but ncL all] living things. Label the proceeses: A 15 gm 1.2.3 _ lone hesL Nurdl. E. '15 called {one besr'wurdb. C is called {phraeeiu D is caileti acne beet ward: . gluon—1|: Ivii-"W“ ruufl'i'g PH CUI— mail-titan [5.5+]: nL'II'll (gr uH-mr Pl'uflf-h} F C’ \\ 1'? :1 uagd cafmiarfi 1" +run5'i'fir syshm afléL'fihfl. _ C 01. real. than. H10 [:1 “ambit-'1 AT P {ac-robin.) Page If} Name thfirm i. mild-1:5. SUSfikincirfi fiufi5lhnn5- ll. {1 pt} Circle one letter. Of the otepo depicted in question 10, which sLep produces the most ATP or GTE? A E C D 12. {3 pt; 1 pt par blank filled correctly} Coneider the following: A. USE undergraduates taking midterma B. laetlt acid bacteria C. oyanohaeterie growing in a lake at noon D. none of the above Write one. two or three letters in the blanko to indicate which organisms fit the fleecription given. live without making ATP. make most of their ATP by using ET? synthese. make all their ATP without using AIP synthase. 13. {1 pt; no partial credit} CH4_CG*CGU- r WAUH + H‘ -* Cflg—CHDH—CUD ~ fihD' pyruvate leetere Let A " lactate Let E = NAN Let C = EADH Let D e pyruvate. Fill in the blanks with A. B, C or D. In the {onward reaction shown above is REDUCED to form and is DXIDIZED to form . Page 1 I 1iJ'qr'rite yeur name er USC ID number here INSTRUCTIONS FOR MULTIPLE CHUICE (except Question 4e}: Circle the letter at the (me best answer. SPELLING CUUNTS. BISC SHUL Intreduetien to Mierehielegy MIDTERM 2 March 23, lflflfi Question 1 (T paints] Questien 2 {5 paints} Questien 31:25 paints} Question 4 {6 paints} Questien 5 {'3' paints] 5-10 7 pt p. ? 11-13 9 pt 9. 3 14-15 ? pt p. s 1 Susskmd'fz 1v—23 ? pt p. 10 . o'tut’éhone- 24:23 6 pt p. 11 29-61 Ept p. 12 32—33 8 pt :9. 13 'I‘UTAL {we eem'rs} BISCSUUL Micitemi 2. '3i28ffl5. 13.? of 13. Mutiple choice {except 4:}: Circle the leller of the one best answer. Your initials 5- [2 pt; DD partial credit] Write the scientific name of a cellular organism that causes meningitis. Your answer must be spelled and formatted correctly in order to reeeive credit. T. [i pt; as partial credit] Fill in each blast with a taxonomic cateqery. In a scientific nameJ the first word refers to the and the second word refers to the .E. :1 pt} was originated the binomial system for scientific names of organisms? {You may give either the individual's Latin name or theuneme in the individual's native language.} 9. [2 ptl Fill in the blanks. LIST IN DESCENDZNG GEDER the major taxonomic categories from phylum to species. (An answer must be in the proper place to receive creditfi phylum 1} 2i 3: 4i species 1D. {1 pt: Two bacterial strains that show >5fli DNAHDNA hybridization {relative to the eontroi} are Considered to be members of the same species. Circle True or False BISC3GUL. Midlenh 2- EIZSIDS. p. E of 13. MnIipEe choice {except 4c}: Circle the letter nfthe one best answcn Yom‘ initiais 1'5. {5 pt: 1n the first column, list the :5 properties that are used to classify viruses {in enough detail to make clear what they mean}. In the seconi‘l column, specify those properties Ear HIV. VIRAL PREPERTH HIV 12. :2 pt] Suppose we have the following results when 10 phenotypic traits are tested for two strains uf bacteria. A and E. Trait Strain A Strain E l + — 2 4- _ 3 + + 4 + + 5 + + E + — T — + s + + E e + 10 - + {ail Fill in the blank with s BEEN-1A1. number. E'he similarity coefficient for A and E Ls Us} Based on the similarity coefficient. Strains A and. E are 'inemtrers of the same species. Circle True 'or False 13'. [1 pH Fill in the blank with a number. The current estimate {cited by Prof. Csrocj is that eukaryotes arose shout years ago. I BISCBUGL. Midterm 2.. HERE'S. p. 9 Elf l3. Mutiple ehe‘ine {except 41:]: Circle the letter cf the enebest answer. YDLII initials 14. {5 9:: Suppose we have the fcllcwieg properly aligned DNA sequences, which are to be used [or phylcgenetic analysis: A CTCACCATCGG E TTCGCAATTRIS C TTCACCAGTCC L1 CTCGCCAGCCC {a} The two most clcsely related organisms are a. A and B h. A and C c. Rand D :1. El anal: e.BaedD ' f. C and D {h} The tee most distantly related ctgsnisms are a. A ends. b. hand C c. A and D d. E! and C _‘ e. B and u f. C and D (c: The distance, d, between A and E! is a. 6 s. ':I c- 4 d. 3 e. 2 E. 1 15. {1 pt; nc partial creditll What flees HI‘».F stand fer? 16. {1 pt: As a. general rule, RNA viruses encode a reverse transcriptaae. Circle True or False BISCE‘DHL. Midterm 2-. SEEMS. p. 11] of 13'. _ Mun-ole choice {except 4:}: Ciro’le the IeLtcr ofthe one best answer. Yflur initials 1?. :1 pt] If the single—stranded genome of RNA phage T directly encodes the phage proteins. then T is a a. l+J strand'virus b. {—} strand Virfls 13. :1 pt} Replication of a single—stranded virel genome always involves synthesis of a complementary strand of nucleic acid. Circle True or False 19. :1 pt} The anti—HIV drug AZT most closely resembles a. adenosine b. deoxyadenosine e. eytidine d. deoxyoytidine e. guanosine f. deoxyguenonine ' g. nridine n. deoxythymidine 2D. {1 pt} For HIV; the viral genome is synthesized by a. RNA Pal I b. RNA Pol 11 t. REA Fol IEI d. RNA—dependent RNA polymerase e. Reverse treneorlptase f. DNA-deoendent DNA polymerase 21. ll pt} All viruses have at Least one a. envelop b. envelope :. glyecptotein d. host e. lysis protein 22..£1 pt} Fill in the blank with one word. For all viruses, the term for a mature virus particle is . 23. (I pt:.no partial credit: Fill in the blanks with numbers. An icosahedron has fates. .vertices, end edges. p. 10. BISCSUUL. Midterm 2-. SEEMS. p. l l of'13. Mutipis choice {except 4:}: Circle the letter :1me one best answer. Your initials 24. [1 pt} Fill in the blank with a single word. Lysogeny is to h as is to herpesvirus. 25. :1 pt} The process by which L DNA is set out of the nest-chromosome is sailed a. splicing h. lysis on excision d. disjunction e. disintegration 26. [1 pt} The process by which a temperate phage leaves the lysegenio state and returns to lytie growth is called a. reversion h. induction or excitation d. activation 21. {2 pt} Give an example of a protein that is encoded by a phage gene the: is expressed during iysogeny. Your answer should make Clear what the ptotein does. 23. :1 pti which of these is the smallest nucleic—ecid—centeining infectious agent? a. M13 h. nucleoeapsid o. THU d. vipoid BISC3UUL. Midterm 2. 3HEFU5. p. 12 of13. Mulipls choice {except 4:}: Circle the letter 'ofths one best answer. Your initials 29. {2 psi This picture concerns measles virus. [a] The first step is called a. attachment h. adsorption c. adsorbticn d. absorption e+ absorbticn is} The second step illustrates a. membrane fusion b. exocytosis c. endocytosis d. budding ,4 nan-er 3'3- E3 Pt? a lens. lens liaise”... "“3333" time ago . ' mummmue e x e L/ (93’ @ 6;? I. . v Ehllllafilnsls shale-armhulit hiL'EBriI-lm 1a] Current evidence indicates that a single such event accounts for all extant chloroplasts. Circle True or False [bi Fill in the blank with the one best word. The picture illustrates the theory for the origin of chloroplasts. to} Chloroplasts, like mitochondria, contain a genome separate from the nuclear genome. Circle True or False Hi. {1 pt: BRIEFLY explain what is awkward about the term "sexual renroduction'I when applied to eukaryotic microorganismsi p. 12. BISCEEIUL Midtenn 2. EFEBIUIS. p. 13 of 13. Mutiplo choice {except 4o}: Circle the lottcr'ef the one best assent Your initials 32. {l pti All photosynthetic eukaryotes carry out oxygenie photosynthesis. Circle True or False 33. {1 pr: What organisms literally live in glaSE hoeses? a. diatoms h. foraminifera .c. radiolarla do water molds 34. {2 pr} Three groups of eukaryotee-are amitochondrial {lack mitochondria]. {ai.Name an amitochondriai eukaryote. {You may give a full scientific name or any correct texcnu} {b} What is_the most relevant ecological property shared by nearly all emitochundrial eukaryotes? 35. [1 pt: According to the Three Domains scheme. how many domains are eukaryntic? a. G s. l c. 2 'J- _| 36. [1 pt} According to the Five'Kingdoms scheme, how many kingdoms are eukaryotic? l 2 3 fl 5 (Ullfifl’fll 3?. (1 pt} which of the following would he the BEST evidence that two organisms have a close phylogenetic relationship? a. They-are similar in shape. b. Their rDNfl sequences have many nucleotide differences. 6. Their rDNfl sequences have few nucleotide differences. é. They have the same mol l G+C. 3B. {1 pt} if an organism can reproduce sexuallyr it cannot reproduce asexually. Circle True or False WRITE YOUR FULL HAHE OR USE ID NO. HERE: EISCBflDL Final Exam EIBEDE MULTIPLE CHOICE QUESTIONS: CIRCLE THE LETTER OF THE ONE BEST AfiSWER. DD NOT LIST HERE ANSWERS THAN THE NUMBER REQUESTED- OTHER ANSWERS SHOULD EASILY FIT IN THE SPAEES PRUVIDED. Q PtE Page 1—5 a 7} 5—7 a. _: _ _ a a :1 _ _ u—l|] 10 5 :1—:a1 10 a _ SUSS'K—‘tntig =— u. -.- L l- 15 iucfifioflf 20-2? 9 B 23-25 T 9 25—2? 3 10 )H q :1 29—31 3 12 32-33 1. 11 TOTAL lUU BISCEUUL. Final Exam. SIEHUS. p. 2 of 13. _ Do not list more answers than the number requested. Your usme1 initials. or logo. 1. :1 pt} Which term refers te a symbiotic interactlen in which one species benefits and the other species is neither helped nor hurt? A. Hutualism B. Semi-muiualism C. Commensalism a. Synrhrophy F ., All of the ahcve 2. (1 pt} What is the main source of energy driving primary predeceien in the deep—sea ecosystems sear hydrothermal vents? A. SunlighL E. oxidation of inorganic compounds C. Oxidation of organic compounds D, Heat a 3. :1 pt] FeMoCo is specific for A. Carbon Eixeilon 3. Iron respiration C, Molybdenum respiration D. Nitrogenase 4. [2 pt] Name TWO enzymes that are unique to the fisJOR pathway for autotrophy. Abbreviations are acceptable. 5. [3 pt} Give an example of a mutually beneficial Symbiosis described in Chapter 25. other than the associations involving legumes or tube worms. BREEELY describe what each organism contributes to its partner. EISCEDDL. FineE Exam SEEMS. 53.3 of 13; He not list more answers than the number requested. Your name. initials. er Inge. Eu [3 pt total} The figure at right BIUCEBE. summarizes the. chemistry of a C H O __..._.§.b;amfl$5_ ehemeheteretreph that carries out {1 ‘1: E eerehic respiration {e.g.¢ Heme r . . . , a}! sepiens er Escherichia cell} . 5'1 C 02. E1 EFJTufiflir EV-i'fl'“ .”'1 ll. mthbmnc DL_._.__} H10 red ue‘r‘ln-n ta} [3 pt: Write a few sentences to explain what this figure meene. (What faete deee Lhe figure depict?} {h} 42 pt} Draw er: anele'geus figure to illustrate the Chemistry or the bacterial eymt-innts in the tube worms near deep-sea hydrethermel vents. T. [1. 53-113 Seedlings on the ieft. Iwere inoculated with a fungus, whereas these on the right were not. Ciicle True cu:- Eaise BISCEUflL. Fina] Exam. fifgfflfi. p. 4 nf 13. Be not list mere unaware man the number requested. Yeur mime. inilials, 0r lege. 3. [E pt total: This is an Lg molecule. {a} 11 pt) The shaded regions are R. UL and V“ e. Each ~lDD amino acids lung C. N-Zerminal domains D. A11 Of the nbnve E. None of the above (b: (l pt] The circled portion of this lg molecule is called , Yeur anewer must be properly formalted. to? L4 pt: Briefly explain TWO different functions 0f thE circled martian. HE sure to define and deactibe any molecule that interacts with the circled pcrLien. (Your answers can apply to isct e: ether than the one depictcc.] BISCEUDL. Final Exam. fifflfflfi. p. 5 of 13. Do not list more answers than the number requested. Your name, initials. or logo. s- 16 pts total: The picture shows a class tisotype] of antibody. (a: [1 pt} The 3—letter abbreviation for this ciass is . Your answer must be properly formatted in order to receive credit. {h} {1 or: The number of antlgen—bindlng pockets {sites} in this In (the whole thing} is . (Ci :1 pt] The number of CDRs in this In {the whole thing} is to: i1 pt] This Iq has heavy chainisi called tel :1 pt} As the antibody transverses an epithelial cellr the.entihcfly acquires an additional protein subunit named A. flg-microglobulin E.JcMin C. K chain D. 1 chain E. Secretory piece if: :1 pt} This isotype is most abundant A. In the B cell membrane E. In the T celi membrane C. In mucus L'El H :1 SEI'L'IIITL E. On the surface of mast cells 1h. (4 pt] In the first column. give the three—letter abbreviation for the antibody class iisotypel. Your answer must be properly formatted in order to receive credit. In the second columnIr give the name of the heavy chain. « Llass Heav chain Description First class to appear after immunisation. Important in hypersensitivity and defense against parasitic worms. BISCEUDL. Fina] Exam. fifgfflj. p. a sf IE. Do not list more answers than the number requested. Your name, initials. or logo. 11. {5 pts total, 1 pt pee entry: Fill in the first column of the table. Spelling counts. on not use abbreviations. CELL TEPE FUNCTION DR DESCRIPTION Important in defense against parasitic worms Host abundant professional phagocyte in blood Professional phagocyte derived from monoeyte Releases histamine to initiate the inflammatory response Capable of ADCC [antibody-dependent cellular cytotoxieity} 12. {3 pt} Fill in the first column of the table with a GENERAL TERM for the TYPE of disease or disorder {not a specific example]. Spelling counts. Do not use abbreviations. TYPE DF DISEASE UR DISORDER DESCRIPTIGM Immune system reaces with a self- antigen. Immune system fails-to react with foreign antigens. Immune system overreaCLs with a harmless foreign antigen £e.g. peanuts]. 13. :1 pt: T cells are named for A. Thymus E. Thyroid C. Tolerance D. Texieity E. All of the above 14- 11 Pt! Which type directly hills virus-infected human cells? A. CTL B. Plasma cell C. Th cell D. All of the abave E. Home of the above BISC3UDL. Final Exam. fifgfflfi. p. '1" of I3. Do not list more imswers Lhen the number requested. Yeur name. initials. or legs. 35. [l th Which is an example of vaccination? A. A child who had a case of chickenpox will never get chickenpox again. E. During an eutbreak of disease due to respiratory syncytial virus 1Rfi¥fl. a premature baby in the hospital is given Synagisfit an anti- RSU monoclonal Ah. F) A newborn baby reteives Ab in colostrum. D- A lTULcentury milkmaid with a natural case of cowpex is immune to smallpox. . All of the above. [1.1 F. None of the above. 1E. it pt} Put a chechmerk f in EITHER Column 1 or Column 2 to indicate Whether the description is true for endotoxin or exotosin. ENDDTGKIE EKGTDHIN DESCREPTIGN _ LFS of Gram-negative bacteria. =—— Major pathogenicity EacLDr in dlpntherla. More lethal fl per molEcule or per unit of messi. l?. :3 ptl Write either A or B in the blank to indicate which subuniL of diphtheria toxin has the activity listed. Hinds to e receptor on the surface of the target cell. Enters the cytoplasm of the target cell. ADP—ribosylates a target protein. 13. :4 pt} List 4 anatomical sites whEre normal flora (normal microbietal virtually always occur in healthy adults and list one example of normal flare per site. Give the full scientific name or the genes name as done in the picture of a lady in your textbook (Fig. 2E.l:. Your answers must he spelled and formatted correctly. 19. {3 pt: Eist 3 anatomical defenses [Fifi Line of Defence"h. with enough detaii to clarify how each defense works. p. T [::] EISCfifl-DL. Final Exam. SIWIIS. p. E of [3. Do not list more Rosa-Hers than the number requested. Your name= ioilisls+ or logo. Zfl. [l th So far, the only disease that has been eradicated worldwide by vaccination is A. Chickenpox E. Polio C- Smallyox D. Diphtheria 21. :3 pt} Write EITHER I or II in the first column to indicate whether the description fits MHC class I molecules or MHC class II molecules. CLASS DESCRI PTIDN Displays peptides derived from proteins made outside of the antigen—presenting cell. 22. {5 pt total] r r c a m; when/J F L4 _- “Fr-Vila!» II if: “We'r- 'I Trunk”: r I:,_il —._ NflF- '-" r"ii. E '-'E."\J _ [mind-Inf "' tr" e: r r:“' A is A.NURMAL ceri E is afan . C is afan molecule. D is afao {ONE WORD}. Briefly describe how the normal interaction on the left differs from the abnormal interaction on the right. Why is the abnormal interaction dangerous for the animal or person? What will happee? a D ‘U BISCEIGGL. Final Exam. SEEDS. p. 9 of I3. Do. not list more answers than the number requested. Your. name, initials, or logo. 23. [2 pt] Put a cheekmark 1:“ in EITHER Column 1 or Column 2 to indicate whether the description is true for a primary metabolite or a secondary metabolite. PREMARY SECONDARY DESCRIPTION — Produced by a single or relatively few species. —_ filoohol {ethanol} produetion by yeast. Yield follows growth closely. 24. [2 or total] co3 CDCI— . I Step 1 Wu H c=o H—C=D Step 2 H-C—GH | I ——————————-—~+ | {IE-I] C113 CH3 nyruyate soeteldehyde ethanol is] 11 pt} Which is true fer ethanolie fermentation? A. Step 2 involves NRDH -* MADE 3. Step 2 involves NAo‘-+ nan. {h} {1 pt: Teast heye already produced ATP when they produce pyruvate from glucose by glycolysis. Why don‘t they just excrete pyrovate instead of converting pyruyate to ethanol + C03? 25-. i3 pti Fill in the blanks in first oolumnef the table to give an example of .5 product that is produced industrially using the microorganism lie-ted+ PRODUCT FCIR SALE MICRQGREIHNISM — ”WWW WW —— BISCSfl-DL. Final Exam. SEEDS. p. H] of 13. Do not list more answers than the Weber Equeateti. Your name, initials, or logo, 25. [4 pt: Him, a 20—year—old r.u-oman, suffers from an infected toothjost as she is leaving town for Christmas vacation; Kim's dentist prescribes Pen G, a natural penicillin, but it seems to have no effect at all. After 3 days of misery, Kim switches to emoxicillin, a semivsynthetie penicillin that she finds in her sister’s medicine cabinet. The amonioillin immediately oures the infection and Kim enjoys the rest of her vacation. Fro-vine an explanation for Kim’s ease. Your answer should include explanations of the terms “natural penicillin” and “semi—synthetic penicillin" and a brief explanation of how they are produced. Provide a good. reason why one worked and the other did not. 21‘. :n! gt: After 3 days of taking Pen G and T days of taking amoxioillin, Kim notices that she has the symptoms of a vaginal yeast infection, even though She has not been sexually active lately- Provide a good explanation. Take into aoeount all the words in held- BISCBEPDL. Final Exam. SINGS. p. ll (if i3. Do net list more answers than the number requslud. Your name; initials. or logo. 26. [9 pt totall Strain M594 is an isolate of Streptococcus pneumnniae Ersm s Child Whfl diEd of pneumonia at 20 months. MESH capC' is a spontaneous rough mutant of M594. Pure cultures of these strains were_grown under standard laboratory cenditiens and cells were injected subcutaneously in naive adult mice [*EU celis per mouse]. The results are presented below. Bacterial Strain Colon Type Fate of Mice +1594 cape" D cut of 2:: mice died within 5 days. i The two survivcrs are Mickey and Minnie. la} [3 FL] Provide an explanation for these results in light of what you learned ...
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