chem206 Rapor-10 - ABSTRACT: In this experiment the aim was...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
ABSTRACT: In   this   experiment   the   aim   was   to   investigate   nucleophilic   substitution  reactions.  1-propanol and sulfuric acid were reacted  at high temperature following  S N 2 reaction mechanism. The final product was collected and its refractive index was  measured under refractometer. The result was found to be 1.3840 on average a5t 19   C.  INTRODUCTION: The aim of this experiment was to study nucleophilic substitution reactions. In  nucleophilic substitution reactions of organic chemistry an nucleophile attacks to the  leaving group of a molecule and substitutes with it. This partially positive leaving  group is called an electrophile.  Nuc :  + R-LG   R-Nuc + LG : Rxn1 Nucleophilic substitution reactions which were first studied by Edward D.  Hughes and Sir Christopher Ingold  in 1935 are divided into two mechanisms:  bimolecular and unimolecular. Bimolecular nucleophilic substitution reactions are  called S N 2 reactions and unimoleculars are called S N 1. These two mechanisms are  affected by different and sometimes opposite factors.  In S N 2 reactions, mechanism is called backside attack, which means  nucleophile and electrophile exchange occurs at the same time and configuration of  the molecule changes oppositely.  Figure 1: S N 2 reaction mechanism In S N 1 reactions, mechanism has three steps: dissociation of leaving group  and the rest of the molecule, nucleophilic attack and deprotonation. The lowest step  is called rate determining step. In this step dissociation occurs.At the end of S N reactions, product is in the racemic mixture form.   1
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
N 1 reaction mechanism. Table1: Factor Differences of S N 1 and S N 2 Reactions: Factor  S N S N 2 Kinetics  Rate= k[RX]  Rate= k[RX][Nuc] Substrate     3     2      Leaving group For halogens, I > Br > Cl >> F
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 04/17/2009 for the course CHEM chem206 taught by Professor F.y during the Spring '09 term at Kalamazoo Valley Community College.

Page1 / 11

chem206 Rapor-10 - ABSTRACT: In this experiment the aim was...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online