Chapter 14 Outline

Chapter 14 Outline - Chapter 14 Viral Infections of the...

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Chapter 14 Viral Infections of the Respiratory Tract and Skin Introduction 14.1 Viral Infections of the Upper Respiratory Tract Influenza Is a Highly Communicable Acute Respiratory Infection It is transmitted by airborne respiratory droplets There have been at least 31 influenza pandemics since 1510 The virion belongs to the Orthomyxoviridae family It contains two types of spikes Hemagglutin (H) helps the virion attach and penetrate host cells Neuraminidase (N) helps release virions from the host cell after replication and assembly Influenza A strikes every year and causes most epidemics Influenza B also strikes every year but is less common than type A Influenza C causes a mild respiratory illness but not epidemics A new flu strain evolves every year, requiring development of a new vaccine Complications such as pneumonia or secondary infections occur in infants, elderly, and immunocompromised people Guillain-Barré syndrome occurs when the body damages its own peripheral nerve cells Reye syndrome often occurs in children who take aspirin to treat pain and fever Rhinovirus Infectious Produce Inflammation in the Upper Respiratory Tract Rhinoviruses belong to the Picornaviridae family They are transmitted by airborne respiratory droplets or contact with contaminated objects They are responsible for many cases of the common cold More than 100 different rhinovirus strains can cause common colds Researchers are developing drugs for treating rhinovirus infections Adenovirus Infections Also Produce Symptoms Typical of a Common Cold Adenoviruses belong to family Adenoviridae They induce the formation of inclusion bodies in host tissues They are transmitted through respiratory droplets Infection can cause acute febrile pharygitis, pharyngoconjuntival fever, or acute respiratory disease Any of these can progress to viral pneumonia 14.2 Viral Infections of the Lower Respiratory Tract Paramyxovirus Infections Affect the Lower Respiratory Tract Respiratory syncytial (RS) disease is caused by the respiratory syncytial virus (RSV) It commonly affects children under 1 year of age It infects the bronchials and alveoli of the lungs, causing cells to fuse together into
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Chapter 14 Outline - Chapter 14 Viral Infections of the...

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