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Unformatted text preview: i. Lactose binds to the repressor and tweak it so it cannot remain bound to the promoter , then RNA Polymerase can move in and attach to the promoter and initiate transcription (lactose utilization gene) probably produces lactase or some enzyme. 1. Enzyme breaks this down to glucose and galactose ii. No lactose present – 1. The regulatory protein can come in and bind to the inhibitor. 2. *concentration of sugar that ultimately becomes the on/off switch 4. Eukaryotic Regulation (Chapter 19) a. Two points of regulation i. In the nucleus 1. Regulate the production of pre-mRNA (similar to lac operon) 2. RNA Processing 3. Regulate or control the mRNA prior to leaving the nucleus ii. Cytoplasm 1. Regulate ribosomal subunit (slow down translation) 2. Take mRNA move into cytoplasm and immediately destroy it. 3. Prions- destroy central nervous system-don’t allow the polypeptide to become a tertiary structure. Keep it for long periods of time....
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This note was uploaded on 05/27/2008 for the course BIOLOGY 107 taught by Professor Dr.abbott during the Fall '08 term at UConn.
- Fall '08