Lecture 21 – Molecular Genetics – DNA

Lecture 21 – Molecular Genetics – DNA

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Unformatted text preview: Lecture 21 – Molecular Genetics – DNA A. Structure of DNA 1. Nucleotides (fig. 12-3)- The building-blocks of DNA • Pentose sugar o Deoxyribose in DNA o Has 5 carbons • Phosphate group o Nucleoside triphosphates o Need all three of these to make DNA molecule because they provide the energy o Attached to the 5 carbon and 3 carbon • Nitrogenous base o Thymine, cytosine (pyrimidines) o Adenine, guanine (purines) Chemicals to treat cold sores are purine derivatives 2. 3’, 5’ phosphodiester linkage- Refers to three carbon a nd five carbon- The phosphate group is in betwe en the two sugars’ carbons and a long chain can be • At one end there is a 3’ carbon h at isn’t attach ed, a nd at the other end there is a 5’ c that isn’t attached- Polynucleotide • To m ake one, add on one nucleotide at a time 3. Base p airing- Nucleotides are hydrogen bonded togeth er, but when the nucleotides are bonded to t phosph at e groups that is an ionic bond 5’ 3’-T-A--C-G--T-A- -C-G- 3’ 5’...
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Lecture 21 – Molecular Genetics – DNA

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