Lecture 22 – Protein Synthesis

Lecture 22 - Lecture 22 Protein Synthesis A RNA structure(fig 13-3 DNA has the code for making protein(there are many different sets of

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Lecture 22 – Protein Synthesis A. RNA structure (fig. 13-3) - DNA has the code for making protein (there are many different sets of instructions), but DNA can’t make the proteins - RNA’s function is to make the proteins using DNA’s code - RNA vs. DNA RNA is single-stranded; DNA is double-stranded RNA’s sugar is ribose; DNA’s is deoxyribose RNA uses the nucleotide uracil o RNA’s purines (adenine and guanine) o RNA’s pyrimidines (uracil and cytosine) RNA has a phosphate group (like DNA) RNA is much shorter than DNA; DNA is very long There are different types of RNA B. Types of RNA 1. Messenger RNA (fig. 13-4) - DNA h as the code, the mRNA carries a copy of the instructions for all the proteins by way of a codon - Codon (fig. 13-5) A triplet The first a nd s econd letters ar e usu ally constant for e ach codon, but the third letter c different If there are 21 a mino acids in insulin, you n e e d (21x3) codons to m ake it 2. Transfer RNA (fig. 13-6) Called a n a d a pt er m olecule Picks up the correct a mino acid coded for in the codon Attaches the m to the correct code - Antiparallel a nd co mple m e nt ary - Anticodon
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Antiparallel and complementary On the tRNA - Specific amino acid - Activating enzyme Attaches amino acid to the end of the tRNA Called amino acyl tRNA synthetase 3. Ribosomal RNA (fig. 13-12) - Synthesized in the nucleolus - Has 2 parts Small subunit and large subunit Have to come together and line up on the mRNA, so tRNA deposits amino acids in the
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This note was uploaded on 05/30/2008 for the course BS 130 taught by Professor Smith during the Fall '07 term at University of the Sciences in Philadelphia.

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Lecture 22 - Lecture 22 Protein Synthesis A RNA structure(fig 13-3 DNA has the code for making protein(there are many different sets of

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