Lecture 13 – Glucose Oxidation II – Aerobic Respiration

Lecture 13 – Glucose Oxidation II – Aerobic Respiration

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Lecture 13 – Glucose Oxidation II – Aerobic Respiration 1. Aerobic Respiration - The oxidation of pyruvic acid to yield CO 2 + H 2 O + ATP - Aerobic respiration starts with pyruvic acid - 3 major steps: 1. Formation of acetyl coenzyme A 2. Citric acid cycle 3. Electron transport system a. Mitochondrion 1. Outer membrane 2. Intermembrane space - Important in chemiosmosis 3. Cristae membrane - Important in chemiosmosis - It is much more selective than the outer membrane - Allows pyruvic acid to get through to matrix (has a carrier protein that takes it across) - Allows ATP to cross - Has a carrier protein for proteins - Lacks a carrier for NADH, which influences how much total energy can be obtained from aerobic respiration NADH was from glycolysis (2 were made) 4. Matrix - Contains enzymes to convert PA CO 2 + H 2 O - Pyruvic acid goes into mitochondria (fig. 4-19) b. Formation of acetyl coenzyme A (fig. 8-5) - Look at Dev’s notes, drawing - Decarboxylation in one of the steps PA goes from a three carbon compound to a two carbon compound (called a two-carb fragment)
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Lecture 13 – Glucose Oxidation II – Aerobic Respiration

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