Lecture 36 – Endocrinology I

Lecture 36 – Endocrinology I - 3 Hormones...

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Lecture 36 – Endocrinology I A. Endocrinology - hormones 1. Endocrine system – includes ductless glands; the cells have vesicles that fuse with the cell membrane, releasing the hormone into the interstitial fluid 2. Endocrine glands (fig. 48.3) a) Autocrine – the hormone binds to receptor sites on the cell that secretes it (it activates itself) b) Paracrine – the hormones stay in the interstitial fluid and has an influence on a cell close to it (because that cell has receptors on it, which is how it recognizes it) c) Circulating hormones – A cell secretes hormone into interstitial fluid, which moves into blood. The target is any cell that has to receptors for it d) Neurohormones – a neuron secretes chemicals, which effect the cell next to it (paracrine)
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Unformatted text preview: 3. Hormones – (refers to the chemical being released); a chemical that turns another tissue on or off 4. Exocrine glands – have ducts; salivary glands, mammary glands, sweat glands, liver B. Hormones – classification (fig. 48-2) 1. Peptides – 2 or more amino acids joined together a) Oxytocin (causes uterus to contract during and after labor; causes ejection of milk during breast feeding), antidiuretic hormone (controls water reabsorption in the kidney) – these are tiny, about nine aa; b) Glucagon (increases glucose in the blood if you need it), secretin, calcitonin – about 30 aa c) Insulin, growth hormone, thyroid-stimulating hormone 2. Amino acid derivatives...
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