Cholesterol - Transferase OPO 3 PO 3 3-Gerenyl...

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H 3 C SCoA O H 3 C SCoA O + CoASH Thiolase Acetyl-CoA Acetyl Transferase H 3 C SCoA O O Acetoacetyl-CoA Acetyl-CoA + H 2 O CoASH - O SCoA O O OH CH 3 HMG-CoA HMG-CoA Synthase Isoprene Synthesis 2 NADPH 2 NADP + + CoA - O OH O CH 3 OH Mevolonate ATP ADP HMG-CoA Reductase - O OPO 3 2- O CH 3 OH Phosphomevolonate Mevolonate -5-Phospho Transferase ATP ADP Phospho mevolonate Kinase - O OPO 3 PO 3 3- O CH 3 OH 5pyrophosphomevolonate ATP ADP + P i + CO 2 Pyrophospho mevolonate Decarboxylase OPO 3 PO 3 3- Isopentenyl Pyrophosphate OPO 3 PO 3 3- Dimethylallyl Pyrophosphate Isopentenyl-PP Isomerase Lanosterol Synthesis OPO 3 PO 3 3- Isopentenyl Pyrophosphate OPO 3 PO 3 3- Dimethylallyl Pyrophosphate + PP i
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Unformatted text preview: Transferase OPO 3 PO 3 3-Gerenyl Pyrophosphate OPO 3 PO 3 3-PP i OPO 3 PO 3 3-Farnesyl Pyrophosphate OPO 3 PO 3 3-Farnesyl Pyrophosphate Prenyl Transferase NADPH NADP + +2 PP i Squalene Synthase Squalene NADPH + O 2 NADP + + H 2 O Squalene Oxidocyclase Squalene Epoxidase H 3 C H 3 C CH 3 HO Lanosterol CH 3 H 3 C H 3 C H 3 C CH 3 HO Lanosterol CH 3 H 3 C Cholesterol Synthesis 3 CO 2 NADPH + O 2 NAD + 19 Reactions ER Mb Enzymes HO CH 3 CH 3 Cholesterol...
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