Ch. 18 GeneRegulation9e

Ch. 18 GeneRegulation9e - 1 What is the Central Dogma 2 How...

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1. What is the Central Dogma? 2. How does prokaryotic DNA compare to eukaryotic DNA? 3. How is DNA organized in eukaryotic cells?
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1. Draw and label the 3 parts of an operon. 2. Contrast inducible vs. repressible operons. 3. How does DNA methylation and histone acetylation affect gene expression?
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1. List and describe the 3 processes that are involved in transforming a zygote. 2. Compare oncogenes, proto-oncogenes, and tumor suppresor genes. 3. What are the roles of the ras gene and the p53 gene?
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Chapter 18
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Transcription
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Operon Operon : cluster of related genes with on/off switch Three Parts: 1. P romoter – where RNA polymerase attaches 2. O perator – “ on/off” , controls access of RNA poly 3. G enes – code for related enzymes in a pathway
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Regulatory gene Regulatory gene : produces repressor repressor protein that binds to operator to block RNA poly
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Normally ON Anabolic (build organic molecules) Organic molecule product acts as corepressor binds to repressor to activate it Operon is turned OFF Eg.
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