Unformatted text preview: However, two thermostability variants recovered by R. M ILKMAN from a natural population, whose electrophoretic mobilities were previously thought to be indistinguishable from those of "standard" alleles, are distinguishable from the standard electromorphs by these procedures. These results suggest that the Adh locus, although polymorphic, does not harbor substantial amounts of "hidden" allelic variability. This study also reports the appearance of substantial mobility variation among isogenic lines that can be induced under specific conditions of sample preparation involving the pretreatment of samples with NAD and acetone. However, genetic analysis demonstrates that this variability cannot be attributed to allelic differences at the structural locus, but instead appears to be dependent upon the concentration of the enzyme in a sample. These results are discussed in relation to the distribution of allelic variation at other enzyme loci....
View Full Document
This note was uploaded on 05/31/2008 for the course EEB 121 taught by Professor Dontknow during the Spring '08 term at UCLA.
- Spring '08