eeb121 - However two thermostability variants recovered by...

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Though widely acknowledged and for a long time conceived, the theory of natural selections is largely disputed and not unanimously agreed upon due to a lack of solid evidence and the fact that evolution is too slow a process to be observed in one’s lifetime so is too readily dismissed. Focus in on rapid adaptive changes in genetic structure occuring by the influence of season in some wild species. The direct observation and evidence that was apparently lacking is now achievable. The dispute can be resolved Ninety-six isochromosomal lines of Drosophila melanogaster from a natural population were screened electrophoretically for unusual mobility variants at the alcohol dehydrogenase locus, using a total of eight conditions of acrylamide electrophoresis. No additional mobility variation was found among the 50 "slow" and 46 "fast" mobility lines beyond that detected by standard methods of electrophoresis.
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Unformatted text preview: However, two thermostability variants recovered by R. M ILKMAN from a natural population, whose electrophoretic mobilities were previously thought to be indistinguishable from those of "standard" alleles, are distinguishable from the standard electromorphs by these procedures. These results suggest that the Adh locus, although polymorphic, does not harbor substantial amounts of "hidden" allelic variability. This study also reports the appearance of substantial mobility variation among isogenic lines that can be induced under specific conditions of sample preparation involving the pretreatment of samples with NAD and acetone. However, genetic analysis demonstrates that this variability cannot be attributed to allelic differences at the structural locus, but instead appears to be dependent upon the concentration of the enzyme in a sample. These results are discussed in relation to the distribution of allelic variation at other enzyme loci....
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This note was uploaded on 05/31/2008 for the course EEB 121 taught by Professor Dontknow during the Spring '08 term at UCLA.

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