Caberte, Mae Lyn M.BSN 3-F Group 20 Client Marlon is taking Phenothiazine promazine. What side effectsassociated with Phenothiazines is similar to the side effect of anticholinergic and pseudoparkinsonism? Why should the bloodpressure be closely monitored? What to you tell the client about thecolor of urine? Phenothiazines are used to treat serious mental and emotional disorders, includingschizophrenia and other psychotic disorders. Some are used also to controlagitation in certain patients, severe nausea and vomiting, severe hiccups, andmoderate to severe pain in some hospitalized patients. Chlorpromazine is used alsoin the treatment of certain types of porphyria, and with other medicines in thetreatment of tetanus.Promazine (Sparine) is a medication that belongs to the phenothiazine class of antipsychotics. An older medication used to treat schizophrenia, it is still prescribed,alongside newer agents such as olanzapine and quetiapine. It has predominantlyanticholinergic side effects, though extrapyramidal side effects are not uncommoneither. Phenothiazines can sometimes cause serious unwanted effects. Tardivedyskinesia or tardive dystonia (muscle movement disorders) may occur andmay not go away after you stop using the medicine. Signs of tardivedyskinesia or tardive dystonia include worm-like movements of the tongue,or other uncontrolled movements of the mouth, tongue, cheeks, jaw, body,arms, or legs. Another possible serious unwanted effect is the neurolepticmalignant syndrome (NMS). Signs and symptoms of NMS include severemuscle stiffness, fever, fast heartbeat, difficult breathing, increasedsweating, and loss of bladder control. Rare - Symptoms of neuroleptic malignant syndrome • Confusion (severe) or coma • difficult or fast breathing • drooling • fast heartbeat • high or low (irregular) blood pressure • increased sweating • loss of bladder control • muscle stiffness (severe) • trembling or shaking • trouble in speaking or swallowing The client must also be advised that urine may be dark in color through thecourse of medication. The vital signs, especially the blood pressure, must be
1 monitored because of the risk of irregularities, which may indicateneuroleptic malignant syndrome. What group of drugs has antiemetic properties? What is the route of administration for client who is vomiting? Antiemetic drugs are used to prevent vomiting ( emesis ) in chemotherapy patients and postoperative patients. Aside from the difficulty of maintainingproper nutrition and a healthy weight, chronic vomiting can result in dehydration , which can be a medical emergency. There are many different ways to administer most of the common medications totreat nausea and vomiting, which is especially important if pills are regurgitatedbefore digestion. Some patients may be given a liquid form of the medicine if theycan keep it down. Sometimes medication will be given as a suppository (in therectum) or even as a topical gel on the skin.
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