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Unformatted text preview: BIO 320 - General Genetics Question bank E 1 I. Population genetics 1. The O blood type is due to homozygosity for the i allele at the ABO locus. In a population at Hardy- Weinberg equilibrium for this locus, 9% of people have blood type O. What is the frequency of the i allele in this population? A) 0.18 B) 0.09 C) 0.3 D) 0.81 E) 0.045 2. In a population at Hardy-Weinberg equilibrium for two alleles A and a at a single locus, the frequency of aa homozygotes in the population is 0.49. What is the frequency of the AA homozyotes? A) 0.51 B) 0.03 C) 0.42 D) 0.49 E) 0.09 3. In a population at Hardy-Weinberg equilibrium, the frequency of people affected by a recessive Mendelian condition is 1/1600. What is the proportion of heterozygotes in the population? A) 1/40 B) 1/1600 C) 39/1600 D) 78/1600 E) 39/40 4. In a population at Hardy-Weinberg equilibrium, there are two alleles of a particular gene, B and b . 9% of the individuals in the population are homozygous for the dominant allele, B . What percentage of the population is heterozygous for this gene? A) 16% B) 91% C) 21% D) 42% E) 82% 5. Two alleles of a gene, G and g, are segregating in a population at Hardy-Weinberg equilibrium. The frequency of the recessive allele, g , is 0.60. What is the genotype frequency of homozygotes for the dominant allele, ( GG )? A) 0.40 B) 0.64 C) 0.16 D) 0.48 E) 0.20 6. A dominant and a recessive allele of a single locus are present at equal frequencies in a large population at Hardy-Weinberg equilibrium. Due to habitat loss, the population is reduced in a single generation to less than 50 individuals, and remains at this size for many more generations. What is the most likely consequence of the smaller population size? A) One of the two alleles will be lost from the population - it could be either the dominant or the recessive allele. B) The dominant allele will be lost from the population. C) The recessive allele will be lost from the population. D) Both alleles will remain at the same frequencies as before. E) New alleles will arise in the population. 7. Two isolated populations of a species differ at a single locus. One population has 200,000 individuals all of whom are homozygous for a dominant allele, B ; the other has 800,000 individuals all of whom are homozygous for a recessive allele, b . If the two populations are merged under Hardy-Weinberg equilibrium conditions what will the frequency of bb individuals be in the merged population after 5 generations? A) 0.50 B) 0.80 C) 1.00 D) 0.64 E) 0.00 8. A scenic and impassable canyon has divided a species into two populations: one population has 60,000 individuals and has become fixed for a recessive allele z; the other has 40,000 individuals all of whom now are homozygous for the dominant allele Z . A strip-mining company fills the canyon with mine waste, so the populations can now mix freely. The combined population remains at the same size and at Hardy-Weinberg populations can now mix freely....
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