7BAlimentary viruses continued - Alimentary viruses continued Coxsackievirus A B A typically rashes B internal symptoms Meningitis aseptic A and

7BAlimentary viruses continued - Alimentary viruses...

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Alimentary viruses continued
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Coxsackievirus A & BA – typically rashes; B internal symptomsMeningitis “aseptic” - A and B (summer/fall)Herpeangina –A (mouth/tongue)Hand, foot & mouth disease -AMyocarditis – BOr mild respiratory “cold type” symptoms that often go undiagnosed
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MeningitisMeningitis = inflammation of the meninges surrounding the spinal cord and brainInflammation caused by infection of the fluid surrounding the spinal cord and brain
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CausesBacterial infectionViral infection-headache, stiff neck, fever and general malaise, possibly vomiting, enteroviruses very common cause of viral meningitisFungal infection- less common cause; causes chronic meningitisPhysical injuryCancerCertain drugs
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Bacterial vs. ViralBacterial Meningitisrare cause of meningitismost serious- life threateningmay result in death or brain damage even if treatedViral meningitismost common cause of meningitisusually mildoften clears on its own within 2 weeksComplications - encephalitis
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SymptomsSigns and symptoms develop over several hours or over one or two daysIn anyone over age 2, see sudden onset of:FeverSevere headache (characteristic symptom)Stiff neck (characteristic symptom)Vomiting or nausea with headache (characteristic symptom)Confusion or difficulty concentratingSeizuresSleepiness or difficulty waking upSensitivity to lightLack of interest in drinking and eatingSometimes skin rash
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ENCEPHALITISEncephalitis is irritation and swelling (inflammation) of the brain, most often due to infections.
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Viral Encephalitides: SymptomsMost people have no symptoms.If symptoms are present, they include:FEVER, HEADACHE, VOMITING, STIFF NECK, DROWSINESS, COMA, PARALYSIS, INCOORDINATION, PSYCHOSES
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HepatitisInflammation of the ????Hepatitis infections (A, B, C, D, E,) have different causes and routes of transmissionA/E – fecal/oral transmission (typically acute infection)B/C – “serum” (transfusion, needle stick), sexual transmission, can have acute stage and may become a chronic infection
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HepatitisHepatitis APicornavirus +ssRNAinfectious hepatitis” fecal-oral, foodborne0.5% mortality, not chronic, no cancerHepatitis ECalcivirus + ssRNAnakedenteric” hepatitis, fecal oral, often foodborneMild disease 1-2% mortality; pregnant patient 20% mortality, not chronic no cancerHepatitis BHepadnavirus ds DNAEnveloped – but resistant“serum” hepatitisParenteral or sexual transmission, insidious onset, 1-2% mortality, assoc w carcinoma, cirrhosisHepatitis CFlaviviradea + ssRNAenvelopedpost-transfusion hepatitis, parenteral or sexual t. acute disease subclinical but chronicity with mortality, assoc w carcinoma, cirrhosisHepatitis DDefective RNA virus require Hep B to grow“co-infection” severe1stB, then B&D high mortality
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  • Fall '16
  • Hepatitis A, Hepatitis D, Hepatitis C

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