{[ promptMessage ]}

Bookmark it

{[ promptMessage ]}

week 2 handout

week 2 handout - Megan Lewis [email protected] OH Thursday...

Info iconThis preview shows pages 1–2. Sign up to view the full content.

View Full Document Right Arrow Icon

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
This is the end of the preview. Sign up to access the rest of the document.

Unformatted text preview: Megan Lewis [email protected] OH Thursday 1-2pm York 3010B Handout 2 Last of enzyme calculations, YAY!! + ΔG A←B- ΔG A →B • The ___________ negative the ΔG, the more products formed. • In order to make the rxn favor products over reactants you must couple a rxn with a ΔG that is a large enough negative value so that when you add it to the ΔG of A →B the overall final ΔG is negative. Ex : hydrolysis of ATP → ADP + Pi gives a ΔG=-30.5kJ/mol If the ΔG of A→B is <30.4kJ/mol then the final ΔG will be less than 0 and thus exergonic. • Our body, and in all organisms in fact, have created a “cash” value in Pi. Every Pi that is released from a molecule releases with it energy since Pi actually wants to be free from other molecules. Thus, the ΔG for releasing Pi is a negative value since the production of free Pi is favored over Pi being attached to a molecule such as ATP. • By coupling this exergonic, product favoring rxn with the endergonic, reactant favoring rxn, the 2 ΔG’s are summed and total a new ΔG. If this new number is negative, then reactions of A →B and ATP → ADP + Pi occur since the overall rxn becomes exergonic. • By using ATP’s hydrolysis (breakdown into ADP and Pi) as the coupler, the ΔG becomes negative resulting in the production of B. And in fact, the B to A ratio increases by a factor of ________ . No matter the ’s, as long as the final ΔG value is negative, the product with be produced by a ________ fold increase! • While ATP hydrolysis gives a ΔG of -30.5kJ/mol, the actual ΔG within a cell is between ______ and ________ kJ/mol since the [ATP] is held steady between 500 and 5000 for every [ADP] in each cell. Thus, -47kJ/mol is the minimum amt of energy needed for a cell to remain alive (to allow all of its processes to have enough energy to occur)....
View Full Document

{[ snackBarMessage ]}

Page1 / 4

week 2 handout - Megan Lewis [email protected] OH Thursday...

This preview shows document pages 1 - 2. Sign up to view the full document.

View Full Document Right Arrow Icon bookmark
Ask a homework question - tutors are online