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1 - BIO 320 Lecture 1 Mendelian inheritance Segregation...

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Observation Tall X dwarf Tall Tall & dwarf (3:1) ratio Interpretation TT X tt Tt TT : Tt : tt ( 1:2:1 ) 3 : 1 (self cross of F1 progeny ) Generation Parent (P) Filial 1 (F1) F2 Genotypic ratio Phenotypic ratio (hybrid cross ) BIO 320: Lecture 1 Mendelian inheritance: Segregation & independent assortment 2008 Genetics: The study of variation and its inheritance Gene : Fundamental unit of inheritance (Note: Mendelian genetics was established without knowledge of the physical basis of genes and their mode of inheritance, i.e. it was an abstract conceptual framework ). Allele : An alternative form of a gene. Genotype : An organism's genetic composition or make-up ( The human genome is known to contain about 30,000 genes ). Phenotype : An organism's appearance ( This is a function of the organism's genotype and its environment. For sanity's sake geneticists work with traits that are primarily under the control of genotype ). Heterozygous : H e t e r o z y g ot e s carry different alleles of a gene. For example, the Tt genotype in monohybrid cross shown above.
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