PRACTICE SET 6A. Questions on Lipid Metabolism and Glyoxylate Cycle 1.The hydroxy acid given below can be completely oxidized to acetyl-CoA by beta-oxidation. Write the series of individual reactions that will accomplish this degradation. Then write the overall sum showing how much ATP, CoASH and NAD+is required and how much NADH, acetyl-CoA, etc., are produced on a per molar basis. Use structural formulas for all substrates and products and standard abbreviations for cofactors (e.g., NAD+, ATP); balance all equations. 2. Calculate the netnumber of moles of energy-rich phosphate (ATP equivalents) that should be produced when one mole tricaproin is oxidized in liver mitochonridria completely to CO2and H2O via beta oxidation and the carbons of glycerol are oxidized to CO2. Show all calculations. 3. When one mole of arachidonic acid is oxidized to CO2and H2O by β-oxidation and the Krebs cycle, how many moles of NADH, FADH2,ATP, and CO2are produced? Arachidonic acid is a C 20 fatty acid with double bonds at carbons 5, 8, 11, 14. CCH2HH3COHCCH(CH2)4HCOO-CH2OCHOCH2OCCCOOO(CH2)4(CH2)4(CH2)4CH3CH3CH3
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