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Lecture 11 - The Cellular Basis of Human Metabolism. Part 3 - Digestion and Absorption in the Inte

Lecture 11 - The Cellular Basis of Human Metabolism. Part 3 - Digestion and Absorption in the Inte

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1 The Cellular Basis of Human Metabolism. Part 3: Digestion and Absorption in the Intestinal Tract Biology 1F25 for Biology Non-Majors Lecture 11 Background Reading Textbook, Chapter 8 The People Who Prepared This Lecture Harry Peery Jeff Stuart The Duodenum
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2 First Problem: Protect against HCl If HCl from the stomach is not neutralized, it will eat holes in the intestinal tract. NOT GOOD! Brunner’s glands secrete copious amounts of mucus to protect the first part of the duodenum. Second Problem: Neutralize the HCl In response to HCl, the intestinal hormone prosecretin is released by S cells into the intestinal lumen. – It is activated by HCl to become secretin – Secretin is absorbed through the intestinal wall and does the following: It inhibits gastric secretion It stimulates the production of a fluid high in NaHCO 3 (sodium bicarbonate) by the pancreas Relationship of Stomach, Pancreas and Liver Liver Gall Bladder Common bile duct Duodenum – 1 st part of small intestine Stomach Pancreas and pancreatic duct Spleen Left kidney Branch of hepatic portal vein coming from both stomach and pancreas
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