Lecture 15 - Leptin - Lecture 15 Background Reading...

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1 Leptin Biology 1F25 for Biology Non-Majors Lecture 15 Background Reading Textbook, Chapter 8. The People Who Prepared This Lecture Harry Peery Jeff Stuart Fat, fat cells, energy, reproduction and human biology The Story of Leptin
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2 Fat vs. glycogen or protein Energy density Fat = 9 Cal/g Protein = 4 Cal/g Glycogen = 4 Cal/g Fat vs. glycogen: Hydrophilic vs. hydrophobic Fat repels water; stored unhydrated Glycogen attracts water; stored hydrated Fat vs. glycogen: the bottom line For equivalent energy storage need 10X as much glycogen as fat! *120 lb female with 20% body fat (24 lbs) would weigh >300 lbs if same energy stored as carbs! Just how much energy is in fat? 120 lb person with 20% body fat (= 24 lbs) 24 lbs ~ 11 kg ~ 11,000 g Remember: 1 g fat contains 9 Cal 9 x 11,000 = 99,000 At 2000 Cal/day this is enough for almost 50 days!
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3 Fueling the starving body Days 1-2: glycogen stores are used up Days 2-50+: fat stores are used Days 5-50+: protein is used; but not all protein can be utilized Question: how does the body maintain energy homeostasis? 1 Big Mac = 590 Cal
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This note was uploaded on 06/10/2008 for the course BIOL BIOL-1F25 taught by Professor Peery during the Spring '08 term at Brock University, Canada.

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Lecture 15 - Leptin - Lecture 15 Background Reading...

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