Lecture 16 - Aging - Lecture 16 Background Reading...

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1 Aging Biology 1F25 for Biology Non-Majors Lecture 16 Background Reading Textbook, Chapter 17, especially pages 370-372. The People Who Prepared This Lecture Harry Peery Jeff Stuart How Long Can We Live? De Grey wrote The Mitochondrial Free Radical Theory of Aging (1999) and more recently Ending Aging (2007). University of Cambridge biogerontologist Aubrey de Grey says 1,000 years or more.
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2 Dogbert takes a more conservative view Bacon will shorten your lifespan because of its high cholesterol, its high sodium (which leads to hypertension), its nitrites and nitrates which are carcinogens when converted to nitrosamines by the HCl of the stomach, and the high levels of free radicals that can be generated. In some, disease and aging come prematurely… Auguste Deter, 51, in 1901 the first patient with the disorder that Alois Alzheimer (below left) described in 1906 and a sample of her amnestic handwriting (below). …or at the height of one’s career… Lou Gehrig two years before he came down with the disease that today bears his name. He was 37 when he died. …or later in life b&w photos by Harry Cutting Artist Norman Rockwell in Arizona in his 70s
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3 C. elegans and the genes that regulate aging tiny worm lifespan of about a month ~1000 cells It can assume a dauer state (hibernation-like) Cynthia Kenyon Discovered in 1993 that a single gene mutation could double the life
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This note was uploaded on 06/10/2008 for the course BIOL BIOL-1F25 taught by Professor Peery during the Spring '08 term at Brock University.

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Lecture 16 - Aging - Lecture 16 Background Reading...

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