Lecture 27 - Oncogenes

Lecture 27 - Oncogenes - Lecture 27 Background Reading...

Info iconThis preview shows pages 1–4. Sign up to view the full content.

View Full Document Right Arrow Icon
1 Oncogenes Biology 1F25 for Biology Non-Majors Lecture 27 Background Reading Textbook, Chapter 19. The People Who Prepared This Lecture Harry Peery Alan Castle To Summarize: Evidence for Multiple Step Cancer Development Cytological Evidence: Cancer develops through a series of stages as evidenced by tumour cytology. Biochemical Evidence: Cancerous cells produce several proteins not usually produced by non-cancerous cells from the same tissue.
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
2 To Summarize 2: Work with the Rous sarcoma virus led to the discovery of the first oncogene called “ src ”. Oncogene, a gene that contributes to cancer. Later studies showed that all animals have normal forms of these genes. Why do we have more than 200 proto-oncogenes? Proto-oncogene Signal Transduction Promotion of cell division
Background image of page 2
3 Proto-oncogene Signal Transduction Pathway 1. Growth factors bind to… 2. Growth factor receptors that pass a signal to… 3. Signal transduction proteins that pass a signal to… 4. Transcription factors that control genes that produce proteins that stimulate…
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full Document Right Arrow Icon
Image of page 4
This is the end of the preview. Sign up to access the rest of the document.

{[ snackBarMessage ]}

Page1 / 12

Lecture 27 - Oncogenes - Lecture 27 Background Reading...

This preview shows document pages 1 - 4. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online