Lecture 30 - Tumour Growth

Lecture 30 - Tumour Growth - Lecture 30 Background Reading...

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1 Tumour Growth Biology 1F25 for Biology Non-Majors Lecture 30 Background Reading Textbook, Chapter 19. The People Who Prepared This Lecture Harry Peery Alan Castle Last lecture: The mutant allele of a tumour suppressor gene is recessive; two mutations which result in the loss of function of both gene copies are required for a gene to contribute to cancer. The second mutation is frequently a deletion of part of the chromosome carrying the tumour suppressor gene. Mutations observed in colon cancer: seven independent mutations. Based upon the observation that cancers frequently show different mutations, we conclude that cancer is a group of related diseases.
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2 Last lecture: Human cells eventually senesce and die. One of the potential causes of cell death: massive damage to the chromosomes after deterioration of the ends of the chromosomes, “telomeres”. Telomeres are formed and maintained by an enzyme called “telomerase”. Last lecture:
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Lecture 30 - Tumour Growth - Lecture 30 Background Reading...

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