Lecture 33 - BRCA1 and BRCA2

Lecture 33 - BRCA1 and BRCA2 - Lecture 33 Background...

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1 BRCA1 and BRCA2 Biology 1F25 for Biology Non-Majors Lecture 33 Background Reading Textbook, Chapter 19. The People Who Prepared This Lecture Harry Peery Alan Castle Last lecture: How do we determine whether or not any characteristic has a genetic basis? First indication: Higher chance of occurrence of the characteristic in a family when compared to the whole population. However, does not prove that there is a genetic basis for the characteristic. Higher chance can be explained by environmental influences (physical or sociological environment).
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2 Last lecture: Breast cancer is not a single disease : it can occur in different breast tissues; it can be unilateral or bilateral; cancerous cells from different patients can have different appearances; breast cancer can be associated with different cancers; onset can be early or late . Early onset breast cancer shows a familial tendency. Familial tendency does not prove that there is a genetic component. Next step is to look for linkage: association
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This note was uploaded on 06/10/2008 for the course BIOL BIOL-1F25 taught by Professor Peery during the Spring '08 term at Brock University.

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Lecture 33 - BRCA1 and BRCA2 - Lecture 33 Background...

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