bio218_back_exam

bio218_back_exam - Bio218 Exam #1 NAME: SECTION #: Bio218...

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Bio218 Exam #1 NAME: SECTION #: Bio218 - Exam #1 Oct. 21, 2003 Format: CLOSED BOOK / CLOSED NOTES 150 points possible/ 15% of Final Grade Multiple Choice: 60 points total 24 questions @ 2.5 points each One answer Write Answers on Bubble Sheet Definitions: 30 points total 15 questions @ 2 points each Write answer in the space provided Short Answer : 60 points total 5 questions @ 12 points each If I can’t read it, no credit will be received Spelling counts Partial credit possible Logical reasoning important Be brief 1
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Bio218 Exam #1 NAME: SECTION #: Academic Integrity: Dishonesty in any form will not be tolerated. 2
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NAME: SECTION #: Multiple Choice: Fill in answers on scantron sheet only. One correct answer per question. 1. Eukaryotic chromosomes are organized: a. by two groups of proteins, histones and nonhistone chromosomal proteins. b. with histones as the basic unit of organization, an octamer of which comprises one nucleosome. c. using histones due to their positive charges, which aids in their interaction with the charged phosphate backbone of DNA. d. in a unineme fashion, where each chromosome represents a single, continuous double helix. e. all of the above. 2. Which of the following statements are incorrect about DNA structure? a. The two strands of a double helix are complementary and anti-parallel. b. The structure was first predicted by Watson and Crick in 1953 to be arranged as a double- stranded helix. c. The final structure disproved the work leading to Chargoff's rule. d. X-ray diffraction patterns indicated a double-stranded structure with repeating substructure every 0.34 nm along the axis e. none of the above 3. The principle characteristics of nucleotides are: a. a 5-carbon sugar, two different classes. b. a cyclic nitrogen base, five different classes. c. a sulfate group d. they are capable of forming large polypeptides e. a and b 4. E. coli chromosomal replication: a. is bi-directional. b. occurs from multiple origins. c. has sequence-specific origin (termed origin or OriC). d. a and c e. all of the above. 5. In the work of Meselsohn and Stahl: a. the method of DNA replication was found to be semiconservative, indicating that the parental double helix was conserved and directed synthesis of a new double helix. b. the experiment used radioisotopes in conjunction with centrifugation to separate DNA on the basis of size. c. it was found that the DNA, after one round of replication, was of intermediate density d. only one round of DNA replication was needed to confirm the semiconservative model. e. none of the above. 6. Complementary strands of a DNA double helix have opposite chemical polarity but are synthesized in the same direction (replication fork movement). This is accounted for by: a. using a 3'->5' polymerase to synthesize the lagging strand. b. using discontinuous synthesis on the leading strand.
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bio218_back_exam - Bio218 Exam #1 NAME: SECTION #: Bio218...

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