Life Science 2 lecture 4

Life Science 2 - Life Science 2(lecture 4 I The Components of cell membranes II Connecting Cells Together III Moving molecules in and out of

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I. The Components of cell membranes II. Connecting Cells Together III. Moving molecules in and out of cells -------------------------------------------------------------------- I. The Components of cell membrane Cell membrane --> All cells: plants, animals, other eukaryotes, all prokaryotes It functions as a selective barrier. Lipid components of plasma membranes Cholesterol: tends to regulate fluidity in the membrane; control the flexibility of the membrane Membranes have many proteins: integral membrane proteins and peripheral membrane proteins Protein functions in the plasma membrane 1. Transport channels 2. Passing signals from outside cell to the inside 3. Enzyme catalysis (hold different polypeptides together in cell membrane to make functional protein) Beta blockers reduce high blood pressure relieve migraine headaches reduce symptoms of anxiety How? - it binds to plasma membrane proteins that serve as adrenaline receptors --> blocks their functioning Membrane defects can cause disease: Cystic Fibrosis Most common fatal genetic disease of caucasians: 1 in 35 possess at least one copy of the defective gene half die before mid-twenties The bad gene results in a defective chloride channel o leads to buildup of chloride ions in lung cells o causes water to move in via osmosis o removing water from surrounding mucus thickens it, makes breathing hard How do we know tht membrane proteins drift around? mouse cell and human cell (with their respective membrane proteins) --> fuse the two
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This note was uploaded on 06/14/2008 for the course LS 2 taught by Professor Pires during the Spring '08 term at UCLA.

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Life Science 2 - Life Science 2(lecture 4 I The Components of cell membranes II Connecting Cells Together III Moving molecules in and out of

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