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Bacteria and Virus Tables - GramNegative Bacteria Family...

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Unformatted text preview: GramNegative Bacteria Family Moraxella catarrhalis Neisseria (catalase) N. meningitidis N. gonorrheae Sinusitis, bronchitis, PNA, OM Asymptomatic carrier, meningitis Gonorrhea, septic arthritis, PID UTI, newborn meningitis, nosocomial sepsis/pneumonia Pneumonia, lung necrosis, nosocomial UTI Wound inf., septiciemia, UTI Bloody, pusfilled diarrhea Gastroenteritis, typhoid fever Gastroenteritis, paratyphoid fever, osteomyelitis Cholera, nonpus diarrhea Food poisoning, wound inf. Secretory diarrhea Gastroduodenal ulcers PNA, osteomyelitis, burn inf., UTI, endocarditis, corneal inf., ext. ear Opportunistic pneumonia PNA, endocarditis, meningitis, catheters/breathing tubes Peritoneal abscesses (90%) Fecal Fecal Fecal Fecal Fecal Fecal Salt water Salt water Raw meat Food Air, touch Air, touch Air, touch Opportune Opportune Opportune Air Sexual Sexual Air Air Bacillus Bacillus GI tract GI tract GI tract Gi tract Freakin' everywhere Respiratory tract GU, respiratory Bacillus Normal GI flora Normal resp flora Normal oral flora Respiratory tract Genitalia Vagina Bacillus Bacillus Bacillus Coccobacillus Coccobacillus Coccobacillus Respiratory tract Coccobacillus Respiratory tract Bacillus Curved bacillus Curved bacillus Curved bacillus Curved bacillus F.An F.An MAP MAP O.Ae O.Ae O.Ae O.An O.An O.An O.Ae O.Ae O.Ae O.Ae O.Ae F.An F.An O.Ae O.Ae F.An Bird feces Air Ticks Mice, mites Lice, fleas Rat fleas Mite larvae Lice Cat scratch Animals Dogs, ticks Animals Sexual Utensils Gnats Skin touch Ticks Lice Respiratory tract Resp., pharynx Endothelial cells Systemic Systemic Systemic Systemic Mouth Bone Skin Systemic Systemic O.Ae O.Ae MAP MAP MAP MAP MAP MAP GI tract Bacillus F.An Glc GI tract, lungs Wounds, GU GI tract GI tract Bacillus Bacillus Bacillus Bacillus F.An F.An F.An F.An Lac, Glc Glc Glc Glc Normal GI flora Bacillus EMB, MacConkey Darkfield, TCBS Halophilic, TCBS Selective media, 42 Urease breath test Green metallic growth Smells like grapes MacConkey Black on blood agar Chocolate agar, CO, fV/X Requires factor X Clue cells, whiff test Cysteine agar Bipolar stain Bipolar stain IgG staining DNA probe, I stain DNA probe DNA probe Weil Felix (+) Weil Felix () Serologic testing Serologic testing Complement fixation CSF, urine culture Darkfield, RPR, VDRL VDRL & FTA Abs (+) VDRL & FTA Abs (+) VDRL & FTA Abs (+) ELISA, Western blot Necrotizing PNA, gum disease Necrotizing PNA, gums, OM Meningitis, PNA, sinusitis Chancroid lesions on genitalia Bacterial vaginitis Whooping cough Legionnaire's disease, Pontiac fever, atypical PNA Bubonic & pneumonic plague Enterocolitis, lymphadenopathy Tularemia, PNA, typhoid fever Brucellosis (fever, abortions) Cellulitis PID, CJV, perihepatitis, LGV Avian chlamydiosis, psittacosis Pneumonia, meningitis Rocky Mtn spotted fever (RMSF) Rickettsialpox, flulike Epidemic typhus, BrillZinser Endemic typhus Scrub typhus Trench fever (5 days) Angiomatosis (cat scratch fever) Q fever, virallike PNA, hepatitis Erlichosis (RMSF with no rash) Leptospirosis (CSF), Weil's dz. Syphilis, CNS involvement Oral lesions (Bejel) Bone Ulcers (Yaws) Red and blue spots (Pinta) Lyme disease Relapsing fever Respiratory Sexual Diplococcus Coccus F.An Malt, Glc Chocolate agar VCN F.An Glc Chocolate agar VCN EMB (purple) F.An Lac, Glc MacConkey (pink) EMB, MacConkey EMB, MacConkey EMB, MacConkey EMB, MacConkey Respiratory Normal resp. flora Nasopharynx Genitalia, eye Diplococcus F.An Chocolate agar VCN Species Related diseases Transmiss. Location Morphology Aer Ferment Growth media/Test Antibiotics/Vacc Notes Vaccine (YWCA) Q, Ery Cef, AMG Entero bacteriaceae Klebsiella pneumoniae Proteus mirabilis (catalase, Shigella dysenteriae oxidase, Salmonella typhi flagellum [H], capsule [K]) Salmonella enteritides V. cholerae Vibrionaceae V. parahemolyticus (oxidase) Campylobacter jejuni Helicobacter pylori Pseudomonas aeruginosa Escherischia coli Cef, AMG Q (Cipro) Vacc (Ty21) Q (Cipro) Tet Amoxicillin Oxidase (+), LPS endotoxin, pili, IgA protease Oxidase (+), pili, IgA protease hemolysis, indole (+), verotoxin (60S) Fimbriae, pili, colonization factor Indole (), nonmotile Indole (), motile (swarms), HS Shigatoxin (60S), invasive, IgA protease Flagellum (H antigen) Ticarcillin, carbicillin Multiple Ticarcillin MNZ, Clin PCN, MNZ PCN, MNz Aug, 3 Cef Mac Mac, Rif STM, Tet Tet, Rif PCN, Q, Tet Tet, Mac Tet, Mac Tet Tet Tet Tet Tet Tet Tet Tet Tet PCNG PCNG PCNG PCNG PCNG Tet Tet Pseudo Burkholderia cepacea monaceae Stenotrophomonas maltophilia Bacteriodacea fragilis Single flagellum, cAMP, noninvasive Hemolytic toxin Destroys mucus cells Tx: PPI, metronidazole, bismuth Oxidase (+), antiphagocytic capsule, lipid A, flagellum, very Abxresistant Oxidase (+), Catalase (+), very Abxresistant Oxidase (), catalase (+), very Abxresistant Polysaccharide capsule, no lipid A Bacteroid aceae B. melaninogenicus B. fusobacterium Hemophilus influenza H. ducreyi Respiratory Gardnerella vaginalis tract family Bordetella pertussis Legionella pneumophilia Facultative intracellular, penetrative, capsulated Chlamydia trachomatis Yersinia pestis Y. enterocolitica Francisella tularensis Brucella spp. Pasteurella multocida C. psittaci C. pneumoniae Rickettsia rickettsii R. akari R. prowazekii R. typhi R. tsutsugamushii Bartonella quintana Bartonella henseliae Coxiella burnetii Erlichae canis chaffeensis Leptospira sp. Treponema pallidum T. endenicium T. pertenue T. carateum Borrelia burgdorferi B. recurentis Fleas Respiratory, skin Coccobacillus Food, milk GI tract Coccobacillus Ticks Resp., GI, skin Coccobacillus Food, milk, contact GI tract Bacillus Bites Skin, subcut. Coccobacillus Elementary Sexual Genitalia body (EB) EB EB Pleomorphic Pleomorphic Bacillus Spiral Spiral Spiral Spiral Spiral Spiral Spiral Vaccine (Hib), IgA protease, capsule IgA protease, capsule No capsule lactamase capsule, nonmotile, binds to cilia cAMP, insulin, lymphocytes, histamine sens. Facultative intracellular (Ms), hemolysin Oxidase (+), catalase (+), lactamase Needs Ca; F1 capsule Ag, plasmidmediated Invasive, GMP, mimics appendicitis AKA rabbit fever, invades Ms, needs cysteine Goats: melitensis, Cattle: abortus, Pigs: suis NOT intracellular, nonmotile, penetrative Nonmotile, lysozymeresistant Metabolicallyactive particlereticulate body Grows in cytoplasm, very dangerous, Ox 19,2 Ox19 Ox19 OxK NOT obligate intracellular Ted Nugent!!! Endospores, grow within lysozomes Two flagella, renal tubular interstitial necrosis "Sabershin, perf'd palate, Hutchinson teeth" Endemic to Africa, Middle East, motile Tropical regions, motile Latin America, motile Diseases: PNA = pneumonia, OM = otitis media, PID = pelvic inflammatory disease, CJV = conjunctivitis, LGV = lymphogranuloma venerum Antibiotics: Q = quinolones, Ery = erythromycin, Cef = cephalosporins, AMG = aminoglycosides, PCN = penicillins, Aug = amoxicillin/clavulanate (Augmentin), Tet = tetracyclines, Mac = macrolides (azithromycin, Zpack), MNZ = metronidazole (Flagyl), Clin = clindamycin, STM = streptomycin, Rif = rifampin F.An = facultative anaerobe, O.An = obligate anaerobe, O.Ae = obligate aerobe, MAP = microaerophile, Intra = intracellular Aerobic: Spirochetes Obligate intracellular GramPositive Bacteria Related Diseases Pharyngitis (strep throat), skin inf., scarlet fever, S. pyogenes toxic shock, glomerulonephritis S. pneumoniae PNA, meningitis, sepsis, OM S. viridans SBE, brain/liver abscesses S. agalactiae Neonatal meningitis, PNA, sepsis S. faecalis (VRE) SBE, biliary tract infections, UTIs S. faecium SBE, biliary tract infections, UTIs S. bovis SBE, biliary tract infections, UTIs S. equinus SBE, biliary tract infections, UTIs Exotoxin: toxic shock, gastroenteritis, SSSS S. aureus Direct: PNA, meningitis, osteomyelitis, necrotizing endocarditis, septic arthritis, skin Staphylococcus (MRSA) inf., sepsis, UTI (catalase) S. epidermidis Nosocomial infections S. saprophyticus UTIs in sexually active women B. anthracis Anthrax Bacillus (Endospores) B. cereus Food poisoning C. botulinum Botulism, infants from honey Tetanus Clostridium C. tetani (Endospores) C. difficile Diarrhea, pseudomembranous colitis, postabx C. perfringens Gaseous gangrene, myonecrosis Corynebacterium Pseudomembranous pharyngitis (diphtheria) Nonspore diphtheria rods Listeria Meningitis, septicemia, spontaneous abortion monocytogenes Fungilike Nocardia sp. PNA, abscesses in skin, lung, kidney, CNS filamentous rods Actinomyces sp. Eroding abscesses in mouth, lung, GI, vagina Streptococcus (catalase) Nucleic Acid External Traits Family Piroma Picoma Entero Virus Rhinovirus Poliovirus Cocksackia A Cocksackie B Hepatitis A Echovirus Hepatitis E Calicivirus Alphavirus Rubivirus Hepatitis C Flavi's virus Corona virus Human Immunovirus (HIV) Human Tlymph (HTLV1) Rous sarcoma virus Bunyavirus Orthomixovirus Parainfluenza Resp. syncitial (RSV) Mumps Measles Rhabdovirus Arenavirus Filovirus Reovirus (Rotavirus) Human herpesvirus (HHV) 6 HHV 8 EpsteinBarr (EBV) Herpes simplex (HSV)1 HSV2 Cytomegalovirus (CMV) Varicella Zoster Hepatitis B Hepatitis D Molluscum contagiosum Variola Human papilloma (HPV) BK polyoma virus JC polyoma virus Adenovirus Parvovirus B19 Genus/Group Species Aer MAP H'lysis Morphology Cocci, chain Cocci, chain Cocci, chain Cocci, chain Cocci, chain Cocci, chain Cocci, chain Cocci, chain Cocci, clusters Cocci, clusters Cocci, clusters Bacillus (!) Bacillus Bacillus Bacillus Bacillus Bacillus Bacillus Bacillus Bacillus, hyphae Antigens Growth Med Tests Group A Mannitol salt agar LPS Optochin (+) Optochin () Notes Lancet shape Group B Group D Group D Group D Group D F.An F.An F.An F.An F.An O.An O.An O.An O.An F.An F.An (Double zone) Coagulase (+) Novobiocin (+) PCR, Immunofl. Motile Motile Motile Motile, MNZ/Vanco Motile, multiple flagella, LPS Mycolic acid Bacillus, hyphae Catalase (+), Exogenous, sulfas Acidfast Sulfur granules Endogenous Notes Vaccines: Salk (dead), Sabin (alive) Fecaloral route, Norwalk agent Crosses placenta, "TORCHES" (?) Rat virus Shifts: pandemics, animal human "Koplik" spots Travels up nerve from bile: "Negri" No blood/pus in diarrhea Complicates immunocompromised Cubic envelope Superinfects with HBV Viruses Related Diseases Common cold Paralytic poltomeningitis or mild afebrile Coldlike, viral meningitis, herpangina, hand/foot/mouth Viral memingitis, myocarditis Acute viral hepatitis "Cold" rashes, pericarditis, viral meningitis Hepatitis: acute unless pregnant (20% mortality) Viral gastroenteritis (stomach flu) Equine encephalitis Rubella Chronic viral hepatitis Yellow fever, dengue, St. Louis/Japanese encaph, W.Nile Common cold, URI AIDS Tcell leukemia Rous sarcoma (!) California encephalitis, Rift valley/sandfly fever, hantavirus Influenza: A,B,C; A&B have genetic shift, antigen switch Croup in children, bronchiolitis, URI, viral pneumonia Pneumonia in infants <6 months, acute otitis media Mumps: parotid glands, testes, meninges, encephalitis Measels, giantcell pneumonia Rabies Lymphocytic choriomeningitis, Lassa fever Acute viral hemorrhagic fever (Ebola, Marburg) Viral gastroenteritis Roseola Kaposi's sarcoma Mononucleosis, Burkitt's lymphoma Gingivostomatitis reactivation, herpetic keratitis, enceph. Genital herpes, neonatal herpes Asymptomatic or monomucleosis Chicken pox Shingles Acute/fulminant/chronic hepatitis, liver cancer Fulminant hepatitis, cirrhosis Warts Smallpox 6&11: warts, 16&18: cervical squamous carcinoma Mild or asymptomatic Progressive multifocal leukoencephalopathy (PML) URIs, epidemic keratoconjunctivitis (pinkeye) Erythemia infectiosum (Fifth), transient aplastic anemia ss(+)RNA Naked Calici Enveloped Toga Flavi Corona Retro Bunya Orthomixo Paramyxo Rhabdo Arena Filo Reo ss()RNA dsRNA Enveloped Naked Enveloped Icosahedral Complex Naked Icosahedral Herpes dsDNA Hepadna Pox Papova Adeno ssDNA Naked Icosahedral Parvo ...
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