Maas_101507

Maas_101507 - Genomes: What we know . and what we don't...

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© SMaas 2007 Genomes: What we know … and what we don’t know Genomes: What we know … and what we don’t know Complete draft sequence 2001 October 15, 2007 Dr. Stefan Maas, BioS Lehigh U. October 15, 2007 Dr. Stefan Maas, BioS Lehigh U.
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© SMaas 2007 What we know Raw genome data
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© SMaas 2007 The range of genome sizes ! No correlation between genome size and complexity ! No correlation between genome size and complexity
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© SMaas 2007 The difference in genome size of a factor of 100 is difficult to explain in view of the apparently similar levels of evolutionary, developmental and behavioral complexity of these organisms. The mountain grasshopper Podisma pedestris The fruit fly Drosophila melanogaster 18,000 Mb 180 Mb What accounts for the often massive and seemingly arbitrary differences in genome size observed among eukaryotic organisms?
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© SMaas 2007 Complexity does not correlate Complexity does not correlate with genome size with genome size 3.4 × 10 9 bp Homo sapiens Amoeba dubia 6.7 × 10 11 bp
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© SMaas 2007 Complexity does not Complexity does not correlate with gene correlate with gene number number ~31,000 genes ~31,000 genes ~26,000 genes ~26,000 genes ~50,000 genes ~50,000 genes
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© SMaas 2007 Is an Expansion in Gene Number driving Evolution of Higher Organisms? Is an Expansion in Gene Number
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Maas_101507 - Genomes: What we know . and what we don't...

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