Lecture 17 Bio325 Fall 07

Lecture 17 Bio325 Fall 07 - When is transcription of a...

Info iconThis preview shows pages 1–3. Sign up to view the full content.

View Full Document Right Arrow Icon
1 When is transcription of a particular gene induced? • every gene in an organism is under strict transcriptional regulation, by RNA polymerase itself, as well as by the proteins that are required to initiate (or repress) transcription by binding to the promoter or enhancer regions. • some genes are transcribed all the time, in virtually every cell of an organism; these are sometimes called “housekeeping” genes • the transcription of other genes is induced by specific stimuli - temperature, nutrients, toxins, stress, radiation, growth factors, starvation, chemicals, aging, essentially anything you can think of • transcription initiation can occur within seconds or it can take hours or days, depending on the way in which the induction occurs www.promscan.uklinux.net/background.html Regulation of gene expression can occur at any step from transcription through translation: binding of RNA polymerase to the promoter transcription initiation transcription elongation transcription termination RNA processing/RNA stability/nuclear export (mostly in eukaryotes) binding of mRNA to the ribosome translation post-translation modifications (mostly in eukaryotes) transcription translation
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
2 The basic mechanisms of gene regulation were determined in E. coli: example: the lac operon β -galactosidase transacetylase permease in prokaryotes, clusters of genes involved in the same function often share one promoter; this cluster is called an operon
Background image of page 2
Image of page 3
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 06/19/2008 for the course BIO 325 taught by Professor Saxena during the Fall '08 term at University of Texas.

Page1 / 8

Lecture 17 Bio325 Fall 07 - When is transcription of a...

This preview shows document pages 1 - 3. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online