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Biol110-07-FINAL EXAM

Biol110-07-FINAL EXAM - Biol110-2007-Final Exam Name Exam...

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Biol110-2007-Final Exam Name ____________ ______________ Exam #____ Biol110 Cell Biology Spring 2007 Final Exam Monday, June 11 Instructions: Please write your NAME and EXAM NUMBER in every page. Be brief in your answers and make sure to include key words. Each question is worth 25 points, assigned as indicated. Use the backside of the question page for extra writing space, if needed. This is a closed book & notebook exam. There are five questions in this exam, but your grade will be based on the best four answers/scores. Grading: Question #1 ________ Question #2 ________ Question #3 ________ Question #4 ________ Question #5 ________ Total Score (best four) ______ Letter Grade ______
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Biol110-2007-Final Exam Name ____________ ______________ Exam #____ Question #1: Cyclin dependent kinases and the cell cycle CDKs modify different target proteins at different times of the cell cycle, yet at least in yeast, one CDK can be used for the entire cell cycle. How does CDK modify targets with specificity at each of the different stages of the cell cycle? (4 pts) How is the irreversible inactivation of CDK activity accomplished precipitously at key steps of the cell cycle? What are the molecular events in this mechanism? (5 pts) In the wee1 yeast mutant, cells divide prematurely and the resulting cells are small. What regulatory aspect of the cell cycle machinery is not balanced in this mutant? (4 pts)
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Biol110-2007-Final Exam Name ____________ ______________ Exam #____ What is fundamentally different between the cell cycle regulation of fertilized Xenopus eggs versus human eggs during the first rounds of cell division? What is the rationale between the two strategies? (4 pts) In a rapidly cycling Xenopus egg undergoing multiple rounds of cell division, what would happen if you add an inhibitor of protein synthesis: would the rapid cycle be affected and at what molecular stage? (4 pts) How does X-ray damage inhibit the cell cycle? (4 pts)
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