week4quizkey

week4quizkey - 1. Ran can shuttle through the NPC by a....

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1. Ran can shuttle through the NPC by a. Simple diffusion b. Piggy-backing on exportin c. Being a necessary co-factor for importin d. Nft2/p10 importin which binds Ran-GTP e. All of the above 2. Feldherr’s experiment with isolated NPC and gold particles 8-24nm in size showed that a. The NPC allows for all the particles to diffuse with time b. The NPC appears to have two gates c. The movement of particles is highly slowed in the middle of the NPC d. A and B e. All of the above 3. The phenylalanine and glycine residues found on a certain class of Nups a. Promote secondary and tertiary structure formation b. Prevent secondary and tertiary structure formation c. Appear to keep those Nups folded d. A and C e. B and C 4. Which of the following are advantages to having unfolded proteins in the central conduit of the NPC? a. They allow for a rigid meshwork that can accommodate proteins of all sizes b. Strong affinity for karyopherins allows for slow diffusion of specific particles c. They form a filamentous meshwork that restricts free diffusion d. They bind proteins one at a time to allow for specificity 5. After adding karyopherins to cargo, transport through the NPC a. Occurs immediately without any initial lag
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This note was uploaded on 06/23/2008 for the course BIO 110 taught by Professor Rexach during the Spring '08 term at UCSC.

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week4quizkey - 1. Ran can shuttle through the NPC by a....

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