Simon_09072007 - DIET AGING and MIND Neal G Simon Ph D Dept...

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DIET, AGING, and MIND Neal G. Simon, Ph. D. Dept. of Biological Sciences Lehigh University
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Outline: Diet, Aging, and Mind 1. Review 2 B i Ch i A i 2. Brain Changes in Aging 3. Dementias 4 Dietary Interventions: DHEA and Soy 4. 5. DHEA 6. Soy 7. Summary and Conclusions
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Testosterone Steroid Dehydroepiandrosterone Male Female (T) (DHEA) Active PREG S E 2 DHT T AE DHEA Metabolites Androgen Receptor GABA Target System Serotonin Vasopressin INHIBIT ENHANCE ENHANCE ENHANCE GABA A Androgen Site of 5HT 1A 5HT 1 V 1A AVP Receptor Regulated Transcription Action , 5HT 1B , AVP FACILITATION INHIBITION Effect on Aggression
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“I hope I Die Before I Get Old” Pete Townshend The WHO “My Generation” My Generation
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www youtube com/watch?v=zqfFrCUrEbY My generation The Zimmers 2:18 youtube com/watch?v=i0Xknw XqLDo&mode=related&search = The Who 37 secs
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Changes with Aging
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