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20.1.3 Regulation of Blood Glucose Levels-R

20.1.3 Regulation of Blood Glucose Levels-R - 2.1.3...

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2.1.3 Regulation of  Blood Glucose Levels
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Feedback Mechanism Organ  pancreas Hormones •  insulin •  glucagon
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Pancreas Raises Blood Glucose Lowers Blood Glucose Fig. 5-16 High blood sugar promotes insulin release Glucose Glycogen Insulin Insulin-sensitive tissue cells (muscle, kidney, fat) Liver Glucose Glycogen Low blood sugar promotes glucagon release Pancreas Glucagon Maintaining Blood Glucose Levels Normal Blood Sugar
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Extracellular space Cytoplasm Cytoplasm Extracellular space Fig. 5-17 Glucose transporters Glucose transporter Insulin Insulin receptor Glucose What is the role of insulin?
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 body does not produce insulin or  is  unable to use insulin   causes high blood glucose levels  hyperglycemia occurs, but cells  are  starved for glucose  excess glucose found in urine Diabetes mellitus
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Classification of diabetes mellitus  Type 1 diabetes  person is unable to produce insulin
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Fig. 1, p. 162 Extracellular space Cytoplasm Glucose Insulin receptor Glucose transporters Type 1 Diabetes X
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