Vavylonis_10012007

Vavylonis_10012007 - Biophysics of contractile ring...

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Biophysics of contractile ring assembly Dimitrios Vavylonis Department of Physics, Lehigh University October 1, 2007
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Physical processes in cell organization and function: Transport of biomolecules e.g. transport of cargo molecules along neurons by motor proteins diffusion of proteins across the cell Assembly of proteins into structures e.g. polymerization of actin and tubulin packing of DNA in the nucleus Chemical energy Æ work, pattern/order efficiency, robustness important Response to mechanical signals e.g. mechanical forces in the mitotic spindle “Physical biology of the cell” molecular biology molecular biophysics/biochemistry cell biology/biophysics small scales (~ individual molecules) large scales (> thousands of molecules)
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Collaborators Jian-Qiu Wu Department of Molecular Genetics, Ohio State University Thomas Pollard Department of Molecular, Cellular and Developmental Biology, Yale University Ben O’Shaughnessy Department of Chemical Engineering, Columbia University
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Cell Division of Animal Cells Pollard and Earnshaw, “Cell Biology” (2002) ~50 μ m Ring assembly involves ~ 50 or more protein components. How do protein molecules assemble in a ring?
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This note was uploaded on 03/09/2008 for the course BIOS 95 taught by Professor Varies during the Spring '08 term at Lehigh University .

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Vavylonis_10012007 - Biophysics of contractile ring...

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