Lecture 27_linkage slides

Lecture 27_linkage slides - Chromosomal Basis of...

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Chromosomal Basis of Inheritance. Genetic Linkage. Chapter 15 6th ed.; 269-276 7th ed.; 274-281
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Position of a gene on a chromosome = locus (plural loci ) 2 copies (alleles) of each gene per cell; 1 on each homologous chrom. locus of a gene
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At meiosis, alleles segregate when gametes form and chromosomes are separated
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Mendel’s Law of Inde- pendent Assortment: Alleles assort randomly into gametes RrYy makes equal numbers of these gametes: RY, Ry, rY, ry
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Independent Assortment works because the 2 genes are on different chromosome pairs (meiosis)
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There are many genes on each chromosome Linked genes are on the same pair of homologous chrom’s Locus of gene 1 Locus of gene 2
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Linked genes do NOT assort independently in meiosis! Morgan; studying fruit flies (Drosophila) found: 1. How to tell if 2 genes are linked. 2. If linked; how far apart are they?
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wild type : “normal” appearance mutant ; abnormal phenotype. Results from abnormal of a gene.
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Morgan studied 2 genes : gray body (wild type)
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Lecture 27_linkage slides - Chromosomal Basis of...

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