lab 10 renal control[1] - Kelly Lunt MCB 32L 12/7/07 Lab...

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Kelly Lunt MCB 32L 12/7/07 Lab 10: Renal Control of Body Fluids Electrolytes and pH I. Introduction Background: Kidneys are composed of nephrons, which are the functional unit of the kidney and is largely responsible for maintaining proper body fluid volume and composition. The kidney receives a large supply of blood and filters a fraction of it. The blood enters through Bowman’s capsule from the glomerulus, which is a capillary bed. The blood entering the capillaries is under a considerable hydrostatic force thus there is bulk flow of water, electrolytes, and small molecules such as glucose into Bowman’s capsule. In the proximal tubule almost all nutrients and electrolytes are reabsorbed. Water is also reabsorbed because it follows the nutrients and electrolytes. The Loop of Henle descends down into the medulla. Because of different properties that the descending and ascending limbs have, an osmolarity gradient is produced from cortex to medulla. This gradient is created by the countercurrent multiplication. The next section of the nephron is the Distal Convoluted Tubule. Some reabsorbtion occurs here but not as much as in the proximal convulated tubule. The distal tubules dump into the collecting ducts, which pass through the medulla and eventually the bladder. Water is extracted from the collecting ducts because it passes through the extracellular osmotic gradient. The water permeability of the collecting duct is controlled by anti- diuretic hormone. Not only do the tubules absorb substances, they also secrete waste products such as H
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lab 10 renal control[1] - Kelly Lunt MCB 32L 12/7/07 Lab...

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