INFLAMMATION_notes Modified 3-3-08

INFLAMMATION_notes Modified 3-3-08 - INFLAMMATION...

Info iconThis preview shows pages 1–7. Sign up to view the full content.

View Full Document Right Arrow Icon
INFLAMMATION
Background image of page 1

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Nonspecific Body Defenses Intact skin epidermis Intact mucous membranes gasteric juice, acid mantle of vagina, mucus, saliva, tears/lacriminal secretions, urine First line of defense: surface membrane barriers Second line of defense: nonspecific cellular and chemical defenses Phagocytes, inflammatory response, antimicrobial proteins, complement, interferons, fever
Background image of page 2
Phagocytes NATURAL KILLER CELLS – lymphocytes Can lyse/kill cancer cells and virus-infected cells. Do not depend on specific antigen recognition, but detect lack of self cell receptors Do not exhibit a memory response and are non-phagocytic. Secrete inflammatory chemicals and proteins Second line of defense: nonspecific cellular defenses 1. Macrophages Dendritic cells of epidermis, Macrophages of the lungs Kuppfer cells in liver Microglia in the brain 2.Neutrophils Respiratory burst Phagocytosis 3.Eosinophils Weakly phagocytic
Background image of page 3

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
Inflammation reaction of vascular tissue to injury A sequence of specific physiologic behaviors that occur in response to injury by a non-specific agent same in streptoccocal infection & MI Purpose of inflammation Neutralize & destroy the offending agent. Restrict tissue damage/ alert the individual to the impeding threat of tissue injury. Prepares injured area for healing
Background image of page 4
Causes of acute inflammation- All leads to tissue damage Physical damage Trauma, radiation, burns, frostbite Chemical substances Acids and bases Microorganisms Bacteria with exotoxins Other agents Necrosis - infarction Exogenous vs. endogenous
Background image of page 5

Info iconThis preview has intentionally blurred sections. Sign up to view the full version.

View Full DocumentRight Arrow Icon
The inflammatory response Changes in blood flow- we increase blood flow to area,
Background image of page 6
Image of page 7
This is the end of the preview. Sign up to access the rest of the document.

This note was uploaded on 06/28/2008 for the course KINS 2532 taught by Professor Sturges during the Spring '08 term at Georgia Southern University .

Page1 / 22

INFLAMMATION_notes Modified 3-3-08 - INFLAMMATION...

This preview shows document pages 1 - 7. Sign up to view the full document.

View Full Document Right Arrow Icon
Ask a homework question - tutors are online