water_acid_base_balance_2007_presentation

water_acid_base_balance_2007_presentation - Total body...

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Composition of body fluids K+ HPO4- Proteins Water 65% Cl- Na+ proteins Non- Electrolytes Glucose Urea, lipids ICF ECF Electrolytes Water universal solvent 35% Total body water for 150 lb. male = 40L 25% interstitial fluid 8% blood plasma, lymph 2% transcellular fluid - CSF, synovial fluid
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Electrolytes Chemically reactive in metabolism, determine cell membrane potentials, osmolarity of body fluids, water content and distribution Major cations - Na + , K + , Ca 2+ , H + Major anions - Cl - , HCO 3 - , PO 4 3- Functions?
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Water Movement in Fluid Compartments Electrolytes play principle role in water distribution and total water content because of their unequal distribution Water moves by osmosis and filtration under hydrostatic pressure
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Fluid Balance for proper hydration Preformed water Respiratory loss with cold, dry air or heavy work. Perspiration loss with hot, humid air or heavy work
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Regulation of Fluid Intake
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Regulation of output – urine volume ADH
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Sod ium - Homeostasis Al dos terone - “salt retaining hormone” # of renal Na + /K + pumps
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Sod ium - Homeostasis ADH - blood Na + levels stimulate ADH release kidneys reabsorb more H2O, without retaining more Na + Atrial natriuretic peptide – from stretched atria kidneys excrete more Na + and H 2 O, thus BP/volume Others estrogen enhances Na & H2O reabsorption progesterone has diuretic effect
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Disorders of Water Balance Hypotonic hydration deficit of Na + , ECF hypotonic - can cause cellular swelling most serious effects: pulmonary and cerebral edema Fluid sequestration = excess fluid in a particular location
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This note was uploaded on 06/28/2008 for the course KINS 2532 taught by Professor Sturges during the Spring '08 term at Georgia Southern University .

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water_acid_base_balance_2007_presentation - Total body...

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