Midterm3KEY - Neurobiology Midterm III Fall 2007 ZO 488 ZO...

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Neurobiology CODE NUMBER ____________________________ Midterm III, Fall 2007 ZO 488 / ZO 588 Neurobiology Midterm Exam III ZO 488 / ZO 588 **If you find a mistake in this key, please let me know.** TRUE / FALSE (15 points total) 1. TRUE Monoamine oxidase (MAO) inhibitors are one class of drugs used to treat depression. 2. FALSE Genetic factors appear to play no role in causing schizophrenia. **There is a clear genetic contribution to teh incidence of schizophrenia.** 3. TRUE Mice with experimentally reduced numbers of NMDA receptors show changes in social behavior that can be reversed by treatment with dopamine (DA) receptor antagonists. 4. FALSE After dopamine (DA) is released into the synapse, it is enzymatically degraded in the synaptic cleft. **DA action is stopped by reuptake into the presynaptic terminal by DA transporters; in the terminal DA can be enzymatically degraded by MAO.** 5. TRUE Biological clocks involve negative feedback on gene expression. 6. TRUE Neurons of the locus coeruleus send axons to innervate thalamocortical neurons. 7. FALSE The angular gyrus is located at the site where the frontal, parietal, and temporal lobes come together. **The angular gyrus is located at the site where the parietal, temporal, and occipital lobes come together.** 8. TRUE Pyramidal neurons are neurons in the cerebral cortex that project axons to other cortical areas, to the brainstem, or to the thalamus. 9. TRUE Attention can be selectively focused on an area of the visual field without shifting the eyes to focus on that part of the visual field. 10. TRUE Focusing attention in an area can enhance your ability to detect a stimulus in that area. 11. TRUE The response properties of neurons can change depending on where attention is focused. 12. FALSE Neurons differ in their morphology and function, but not in gene expression. **Neurons also differ in gene expression (e.g., which types of neurotransmitter receptors to express or synthetic enzymes for specific neurotransmitters).** 13. TRUE Acetylcholine, glutamate, and dopamine can be either inhibitory or excitatory, depending on the receptors expressed by the postsynaptic cell.
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CODE NUMBER __________________________ page 1 14. TRUE The rate-limiting step in the synthesis of dopamine is the activity of the synthetic enzyme tyrosine hydroxylase (TH). 15. TRUE NMDA receptors are ionotropic glutamate receptors. MULTIPLE CHOICE – Circle ALL correct answers for each question. (13 points total) 16. Prefrontal lobotomy can result in a change in emotions. Which of the following structures are found in the frontal lobe AND are thought to play a role in emotion? A, B
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This note was uploaded on 07/01/2008 for the course NBIO 721a taught by Professor Sancar during the Spring '08 term at UNC.

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Midterm3KEY - Neurobiology Midterm III Fall 2007 ZO 488 ZO...

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